Alpha lipoic acid supplementation ameliorates the wrath of simulated tropical heat and humidity stress in male Murrah buffaloes

Samad, Hari Abdul; Konyak, Y. Y.; Latheef, Shyma K.; Kumar, Akhilesh; Khan, Imran; Verma, Vinay Sagar; Chouhan, V.S.; Verma, Med Ram; Maurya, V. P.; Kumar, Puneet; Sarkar, Mihir; Singh, Gyanendra

doi:10.1007/s00484-019-01750-w

Cited by 5 publications

(3 citation statements)

References 73 publications

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“…All cows had free access to water during the experimental period. proportion to the severity of HS [19]. During HS, there is an increase in heat shock protein HSP-90, which is observed in cattle, buffalo, broilers, sheep and goats [15].…”

Section: Animals and Experimental Designmentioning

confidence: 99%

“…Thus, endocrine secretions can stimulate the synthesis and expression of HSPs in cells and tissues as a protective mechanism; furthermore, HSPs can also have regulatory effects on the immune system. One heat shock protein, HSP-70, is highly inducible and the most sensitive to HS in ruminants, and its expression escalates in proportion to the severity of HS [ 19 ]. During HS, there is an increase in heat shock protein HSP-90, which is observed in cattle, buffalo, broilers, sheep and goats [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Impact of Heat Stress on Blood, Production, and Physiological Indicators in Heat-Tolerant and Heat-Sensitive Dairy Cows

Chen

Shu

Sun

et al. 2023

Animals

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Heat stress affects production and health in cows severely. Since it is difficult to define heat-tolerant animals, studies of response to heat stress are important for understanding dairy cows’ health and production. However, information on the impact of heat stress on various indicators in heat-tolerant and heat-sensitive cows is sparse. This study aimed to investigate the effects of heat stress (HS) on blood, production, and physiological indicators in heat-tolerant and heat-sensitive cows. A total of 43 dairy cows were used from 9 May to 7 August 2021, under Temperature–Humidity Index (THI) measurements that ranged from 65.9 to 86.7. We identified cows that were tolerant or sensitive to HS based on the slope of the response of physiological and production traits against THI during the HS period by using a clustering method. After HS, serum glucose (Glu), cortisol (COR), 5-hydroxytryptamine (5-HT), and interleukin-6 (IL-6) levels of cows in the heat-tolerant group were lower than in the heat-sensitive group (p < 0.05). With THI as the predictor, the R2 for predicting respiration rate (RR) and body surface temperature (BT) in heat-tolerant cows was 0.15 and 0.16, respectively, whereas the R2 for predicting RR and BT in heat-sensitive cows was 0.19 and 0.18, respectively. There were low to moderate, positive correlations between RR, BT, and MY with THI, with Pearson correlation coefficients ranging from r = 0.11 to 0.4 in the heat-tolerant group, and from r = 0.24 to 0.43 in the heat-sensitive group. There was a low positive correlation between VT and THI, with a Spearman correlation coefficient of r = 0.07 in the heat-sensitive group. The heat-tolerant dairy cows had lower MY losses and had lower MY (p = 0.0007) in mixed models. Heat-tolerant cows with low-stress levels, through upregulating RR rapidly, increased their adaptability to thermal environments. They have better thermoregulation capability; the hypothalamic–pituitary–adrenal (HPA) axis regulated the thermoregulatory in animals by releasing a variety of neurotransmitters and hormones.

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Section: Animals and Experimental Designmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impact of Heat Stress on Blood, Production, and Physiological Indicators in Heat-Tolerant and Heat-Sensitive Dairy Cows

Chen

Shu

Sun

et al. 2023

Animals

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“…Galván et al [26] show that metabolites such as glucose are affected by environmental conditions like the time of sampling and the sex of the animals where the average values found were: glucose 75.57 ± 27.5 mg dL -1 in females and 83.70 ± 37.7 mg dL -1 in males, it is mentioned that this may be related to the preparation of the organism in females for their next production stage, results that are consistent with the values obtain in this study were vary between 71.50 -81.10 mg dL-1 , also Ulbrich et al [27], reported that blood glucose decrease with age, going from 100 mg dL-1 in lactating animals to 71 mg dL-1 in weaned animals. Samad et al [28] studied the effect of the inclusion of ALA (32 mg kg -1…”

Section: Effect Of Dietary Supplementation Of Ala On Blood Glucose Levesmentioning

confidence: 99%

Effect of Alpha-lipoic Acid on Productive Parameters and Ruminal VFA Profile in Sheep

Robles‐Rodríguez

González-Dávalos

Domínguez-Hernández

et al. 2022

ARJA

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Aims: The objective of this study was to evaluate the effect of alpha-lipoic acid (ALA) on feed over the productive parameters of sheep, as well as volatile fatty acids (VFA) in the rumen and blood glucose. Place and Duration of Study: The experiment was conducted at the Centro de Enseñanza, Investigación y Extensión en Producción Animal del Altiplano (CEIEPAA), located in Tequisquiapan, Querétaro-México. Methodology: A total of 64 sheep (Pelibuey x Dorset), two months old (32 males and 32 females with an average weight of 20.7 ± 1.3 kg) were used. Animals were housed in 16 pens, 4 animals per pen, and each pen was assigned to one of the 4 ALA inclusion treatments (0, 40, 80, 120 ppm). ALA was mixed with 50 g of ground corn to ensure its consumption; the animals of treatment 0 also received 50 g of ground corn without ALA. Results: Differences in weight gain were observed from day 56 in the animals supplemented with 80 ppm of ALA (P < .0001) and an improvement in daily weight gain (246 g) and feed conversion (P = .05) was shown. Animals treated with 40 ppm of ALA observed lower blood glucose without affecting the productive parameters (P = .05). A lower concentration of VFA was found in the treatment 120 ppm on day 84 (334.2 ± 26.5 vs 260.0 ± 15.7; P = .05). Conclusion: The inclusion of 80 ppm of ALA in the diet of sheep could improve the productive parameters.

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Comparative Assessment of Thermo-Tolerance of Crossbred and Indigenous Cattle Breeds

Singh

Samad

Karthiga

et al. 2021

Climate Change and Livestock Production: Recent Advances and Future Perspectives

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Alpha lipoic acid supplementation ameliorates the wrath of simulated tropical heat and humidity stress in male Murrah buffaloes

Cited by 5 publications

References 73 publications

Impact of Heat Stress on Blood, Production, and Physiological Indicators in Heat-Tolerant and Heat-Sensitive Dairy Cows

Impact of Heat Stress on Blood, Production, and Physiological Indicators in Heat-Tolerant and Heat-Sensitive Dairy Cows

Effect of Alpha-lipoic Acid on Productive Parameters and Ruminal VFA Profile in Sheep

Comparative Assessment of Thermo-Tolerance of Crossbred and Indigenous Cattle Breeds

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