Alpha Linolenic Acid-enriched Diacylglycerol Enhances Postprandial Fat Oxidation in Healthy Subjects: A Randomized Double-blind Controlled Trail

Alpha Linolenic Acid-enriched Diacylglycerol Consumption Enhances Dietary Fat Oxidation in Healthy Subjects: A Randomized Double-blind Controlled Trial

“…The ALA-DAG treatment enhanced dietary fat utilization as energy compared to the TAG treatment in humans. Taken together with our previous data showing increased postprandial total fat oxidation and energy expenditure after treatment with ALA-DAG 11 , these findings suggest that ALA-DAG treatment induces up-regulation of dietary fat metabolism and contributes to prevent visceral obesity. Indeed, significantly decreased fat mass Table 2 and significantly increased dietary fat oxidation Fig.…”

“…Exclusion criteria included the presence of severe disease, surgery within 2 months, taking medication, taking supplements or foods with health claims, premenopausal woman, and food allergy. The sample size was estimated based on our previous study showing that ALA-DAG significantly enhanced postprandial total fat oxidation in 19 subjects 11 . Because the dose and the consumption duration of ALA-DAG in this present study were the same as the previous study, we estimated that a similar sample size was appropriate.…”

“…Previous human studies demonstrated that the long-term consumption of ALA-DAG significantly decreases body weight and visceral fat area compared to consuming the control triacylglycerol TAG 8 10 . ALA-DAG consumption enhances both fat oxidation and energy expenditure in healthy humans 11 . Thus, ALA-DAG consumption could be useful for controlling body weight by maintaining or improving fat and energy metabolism.…”

Modulatory Effect of an Isolated Triglyceride from Fenugreek Seed Oil on of α-Amylase, Lipase and ACE Activities, Liver-Kidney Functions and Metabolic Disorders of Diabetic Rats

“…Previous study showed the amount of linoleic acid detected in FSO, likely to satisfy the essential fatty acid requirement for humans 16,17 . The nutritional value of linoleic acid is due to its metabolism at tissue levels, which produces the long chain polyunsaturated fatty acids and prostaglandins 18 .…”

Production and immobilization of lipase PCL and its application in synthesis of α-linolenic acid-rich diacylglycerol

“…In food products especially monoacylglycerols and diacylglycerols (MAG and DAG, respectively) are frequently used due to their facile delivery to the human body and the simple processability of these compounds in the dietary products. Some very recent studies showed that α‐linolenic acid‐rich diacylglycerol has promising health promotion functions especially in reduction of visceral fat area (VFA), BMI and serum triacylglycerol (TAG) in men and women with overweight (Ando et al, ; Saito, Fukuhara, Osaki, Nakamura, & Katsuragi, ; Saito, Mori, Osaki, & Katsuragi, ; Yamanaka et al, ). Research showed that DAG activated enzymes involved in β‐oxidation in the liver and small intestine (Murase et al, ; Murase, Aoki, Wakisaka, Hase, & Tokimitsu, ).…”