2020
DOI: 10.18006/2020.8(spl-2-aabas).s322.s326
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Alpha(1)-Adrenoceptors Activation Decreases Myocardial Contractility in Newborn Rats

Abstract: Alpha(1)-adrenergic receptors (α1-AR) are found in cardiomyocytes, endothelial cells, and smooth muscle cells of humans and animals. Despite the fact that α1-AR make up 10% of the total number of adrenergic receptors, these receptors also involved in the regulation of inotropic and chronotropic functions of the heart. According to some scientists, the effects of α1-AR activation are not required for the basal contractile function of the heart while other group of researchers believe that α1-AR can be considere… Show more

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