Aloplasty of an ankylosed knee in a patient with severe haemophilia A

Jaworski, Jerzy; Zawojski, Adam; Zdziarska, Joanna; Czernicki, Krzysztof; Wilk-Frańczuk, Magdalena

doi:10.1016/j.achaem.2017.07.008

Cited by 3 publications

(4 citation statements)

References 12 publications

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“…Joint bleeding is the initiating factor in the pathogenesis of HA. After acute joint hemorrhage, it takes about one week for type A cells in the synovial intima composed of macrophage like cells to clear the blood from the joint cavity [7]. Because hemophilia patients are prone to recurrent intra-articular bleeding, the amount of intra-articular bleeding far exceeds the level of synovial tissue clearance, resulting in intra-articular hematocele and blood degradation metabolites deposition in the joint [8].…”

Section: Discussionmentioning

confidence: 99%

“…In the perioperative period of THA and TKA, the monitoring of coagulation factor arthroplasty therapy is mainly determined by measuring Activated Partial Thromboplastin Time (APTT), the activity and concentration of coagulation factor, and the presence of coagulation factor inhibitor [7]. After admission, please consult with hematology department and make a schedule.…”

Section: Perioperative Coagulation Factor Arthroplasty Therapymentioning

confidence: 99%

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Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-Stage Hemophilic Arthritis

Peng¹,

Chen²,

Cheng³

et al. 2022

J Surg Open Access

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Object: To investigate the clinical efficacy of simultaneous ipsilateral Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA) in the treatment of advanced hemophilic arthritis. Method: The clinical data of 8 patients with advanced hemophilic arthritis who underwent ipsilateral THA and TKA in the Second Affiliated Hospital of Chongqing Medical University from January 2018 to may 2021 were retrospectively analyzed, ages are (31.6 ± 6.2) years old (25-38 year). There were 6 cases of hemophilia A and 2 cases of hemophilia B. The preoperative level of coagulation factor VIII was 1.8% ± 1.3%, Partial Prothrombin Time (APTT) was (131.2 ± 35.3). Coagulation factor VIII arthroplasty therapy was used for type a hemophilia during perioperative period, and coagulation factor X arthroplasty therapy was used for type B hemophilia during perioperative period. All patients had informed consent to the treatment plan and were approved by the hospital ethics committee. Harris score before and 0.3-1 year after operation was compared to evaluate hip function, HSS knee score and KSS score. Result: During the follow-up of (1.4 ± 1.1) years, no intra-articular bleeding and skin dehiscence were found in the early postoperative period, and no joint infection, bleeding, prosthesis loosening and sinking were found in the last follow-up. Harris score increased from (16.8 ± 4.4) preoperatively to (77.6 ± 7.1) postoperatively, HSS knee score increased from (41.8 ± 4.2) preoperatively to (76.0 ± 5.8) postoperatively, KSS clinical score increased from (35.6 ± 10.8) preoperatively to (79.2 ± 6.9) postoperatively, The KSS score increased from (22.8 ± 8.4) preoperatively to (72.0 ± 5.9) postoperatively at the last follow-up. The differences were statistically significant (P<0.05). Conclusion: The same side THA and TKA in the treatment of advanced hemophilic arthritis can effectively relieve pain, improve hip and knee joint function, and improve the quality of life, which is a safe and effective measure for the treatment of advanced hemophilic arthritis.

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Section: Discussionmentioning

confidence: 99%

Section: Perioperative Coagulation Factor Arthroplasty Therapymentioning

confidence: 99%

Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-Stage Hemophilic Arthritis

Peng¹,

Chen²,

Cheng³

et al. 2022

J Surg Open Access

View full text Add to dashboard Cite

show abstract

“…Joint bleeding is the initiating factor in the pathogenesis of HA. After acute joint hemorrhage, it takes about one week for type A cells in the synovial intima, composed of macrophage like cells, to clear the blood from the joint cavity [7]. Since hemophilia patients are prone to recurrent intraarticular bleeding, the amount of intra-articular bleeding far exceeds the level of synovial tissue clearance, resulting in intra-articular hematocele and deposition of blood degradation metabolites in the joint [8].…”

Section: Discussionmentioning

confidence: 99%

“…In the perioperative period of THA and TKA, the monitoring of coagulation factor arthroplasty therapy is mainly performed by measuring activated partial thromboplastin time (aPTT), the activity and concentration of coagulation factors, and the presence of coagulation factor inhibitors [7]. After admission, patient is asked to consult with hematology department and schedule tests.…”

Section: Perioperative Coagulation Factor Arthroplasty Therapymentioning

confidence: 99%

Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-stage Hemophilic Arthritis

Chen

Cheng

et al. 2021

Preprint

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ObjectiveTo evaluate the clinical efficacy of simultaneous ipsilateral total hip arthroplasty (THA) and total knee arthroplasty (TKA) in the treatment of advanced hemophilic arthritis. Methodthe clinical data of 8 patients with advanced hemophilic arthritis, with ages of 31.6±6.2 years (ranging from 25-38 years, who underwent ipsilateral THA and TKA at the ** Hospital from January 2018 to May 2021 were retrospectively analyzed. There were 6 cases of hemophilia A and 2 cases of hemophilia B. The preoperative level of coagulation factor VIII was 1.8(±1.3)%，activated partial prothrombin time (aPTT) was 131.2 (±35.3) s. A comparison of the Harris score before and 0.3-1 year after operation was performed to evaluate hip function, American hospital for special surgery (HSS) knee score and American Knee society score (KSS) score. ResultDuring the follow-up period of 1.4 (± 1.1) years, no intra-articular bleeding and skin dehiscence were found in the early postoperative period, and no joint infection, bleeding, prosthesis loosening and sinking were found in the last follow-up visit. The Harris score increased from 16.8 (± 4.4) preoperatively to 77.6 (± 7.1) postoperatively, HSS knee score increased from 41.8 (± 4.2) preoperatively to 76.0 (± 5.8) postoperatively, the clinical KSS increased from 35.6 (± 10.8) preoperatively to 79.2 (± 6.9) postoperatively. The KSS increased from 22.8 (± 8.4) preoperatively to 72.0 (± 5.9) postoperatively at the last follow-up visit. The differences were statistically significant (P < 0.05).ConclusionsIpsilateral THA and TKA in the treatment of advanced hemophilic arthritis can effectively relieve pain, and improve hip and knee joint function, as well as the quality of life, and can thus be recommended as a safe and effective measure for the treatment of advanced hemophilic arthritis.

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Terapia manualna po alloplastyce stawu kolanowego u pacjenta z artropatią hemofilową w przebiegu hemofilii A – studium przypadku

Byra

Jaworek

2019

Acta Haematologica Polonica

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StreszczenieWstępStaw kolanowy jest jednym z najczęściej zajętych przez artropatię hemofilową, a zabieg alloplastyki stawu kolanowego jest leczeniem z wyboru w przypadku zaawansowanych zmian zwyrodnieniowych. Celem pracy było przedstawienie kompleksowego postępowania fizjoterapeutycznego, ze szczególnym uwzględnieniem terapii manualnej, u pacjenta z artropatią hemofilową w przebiegu hemofilii typu A, u którego została wykonana alloplastyka stawu kolanowego.MetodykaMężczyzna, lat 49, po zabiegu alloplastyki stawu kolanowego lewego, z artropatią hemofilową w przebiegu hemofilii A, został poddany 6-tygodniowej rehabilitacji. U pacjenta zastosowano metody terapii manualnej, ćwiczenia usprawniające oraz fizykoterapię. Oceny postępów rehabilitacji dokonano, stosując: kwestionariusz WOMAC, test Timed Up and Go (TUG test), pomiar goniometryczny zakresu ruchu stawów kolanowych, ocenę siły mięśni zginaczy i prostowników kolana w skali Lovetta, ocenę dolegliwości bólowych w skali VAS.WynikiUzyskano wzrost siły mięśniowej oraz poprawę zakresu ruchu stawu kolanowego. W wyniku terapii poprawie uległa stabilność dynamiczna oraz stan funkcjonalny pacjenta (TUG test poprawa o 35%, skala WOMAC o 32%). Dolegliwości bólowe uległy zmniejszeniu z 9 na 3 w skali VAS. Uzyskano wydolny chód. Usprawnianie przebiegło bez powikłań.WnioskiFizjoterapia, w tym terapia manualna, u pacjenta z artropatią hemofilową po zabiegu alloplastyki kolana, jest postępowaniem skutecznym i bezpiecznym.

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Aloplasty of an ankylosed knee in a patient with severe haemophilia A

Abstract: Material and methods M. T., was a 40 year old male with severe haemophilia A without inhibitor and generalized secondary haemophilic a c t a h a e m a t o l o g i c a p o l o n i c a 4 8 ( 2 0 1 7 ) 2 1 2 -2 1 6 a r t i c l e i n f o Article history:

Cited by 3 publications

References 12 publications

Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-Stage Hemophilic Arthritis

Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-Stage Hemophilic Arthritis

Analysis of the Early Clinical Effect of Simultaneous Ipsilateral Total Hip and Knee Arthroplasty in the Treatment of End-stage Hemophilic Arthritis

Terapia manualna po alloplastyce stawu kolanowego u pacjenta z artropatią hemofilową w przebiegu hemofilii A – studium przypadku

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