Alopecia Universalis, Onychodystrophy, and Total Vitiligo

Demis, D. Joseph

doi:10.1001/archderm.1963.01590200083017

Cited by 35 publications

(13 citation statements)

References 13 publications

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“…An association between onychodystrophy and vitiligo with alopecia areata is also established [Christianson et al, 1956;Lerner, 1961;Demis and Weiner, 1963], Endocrine dysfunction which sometimes accompanies the vitiligo-alopecia areata complex [Lerner, 1959;Bor et ah, 1969] has been claimed to cause such nail changes via disturbance of the keratin formation. The present case does not support this hypothesis since clinical and endocrinologic evaluation failed to reveal hormonal imbalance.…”

Section: Discussionmentioning

confidence: 99%

“…Several authors have drawn attention to the association of vitiligo with other skin diseases such as alopecia areata [Lerner, 1961;Demis and Weiner, 1963;Fields et at., 1971;Calm, 1974]; scleroderma [Christianson et at., 1956;Tuffanelli and Winkelmann, 1961;Lerner and Sansing, 1973], and certain autoimmune diseases [Lerner, 1959;Bor et ah, 1969], This report deals with a 39-year-old patient who exhibits unique coincidence of five dermatological disorders: vitiligo, alopecia areata, onychodystrophy, lichen planus and widespread, localized scleroderma of uncommon morphology.…”

Section: Introductionmentioning

confidence: 99%

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Coincidence of Vitiligo, Alopecia areata, Onychodystrophy, Localized Scleroderma and Lichen planus

Brenner¹,

Diem²,

Gschnait³

1979

Dermatology

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The unique coincidence of five dermatological disorders, which occurred in a 39-year-old patient, is discussed. The clinical and laboratory examination did not reveal a common underlying cause. It is hoped this report will stimulate the recognition of other cases and thus aid in determining whether the coincidence of these disorders is a true association of diseases with a common underlying factor or a rare abnormality.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Coincidence of Vitiligo, Alopecia areata, Onychodystrophy, Localized Scleroderma and Lichen planus

Brenner¹,

Diem²,

Gschnait³

1979

Dermatology

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“…Tissue-specific chalones, glycoproteins, and glycopolypeptides, byexerting a negative feedback control, are thought to regulate the mitotic activity of melanocytes and keratinocytes [154][155][156][157][158][159]. If such chalones are, in fact, a sort of regulatory factor, then the maintenance of a fixed ratio of keratinocytes to melanocytes would require constant and precise balance in the production and utilization of a number of very specific cell chalones.…”

Section: Chalones and Cyclic Ampmentioning

confidence: 99%

Vitiligo and Other Hypomelanoses of Hair and Skin

Ortonne¹,

Mosher²,

Fitzpatrick³

1983

139

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“…In addition, vitiligo has been described in association with alopecia areata, lupus erythematosus, scleroderma, myasthenia gravis, chronic subcutaneous candidiasis, per nicious anemia, atopic eczema, psoriasis, hearing abnor malities, eye involvement and melanoma [2, [12][13][14][15][16][17][18][19][20]. Scat tered reports exist on vitiligo in association with various disorders, e.g.…”

Section: Introductionmentioning

confidence: 99%

Vitiligo and Other Diseases: Coexistence or True Association?

et al. 1994

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In the past, several authors described an association of vitiligo with autoimmune disorders and the presence of different tissue autoantibodies. A review of the literature showed large differences in the results. Therefore, 321 patients with vitiligo (male/female ratio 114/207) were examined to see whether the frequencies of associated diseases and phenomena (i.e. Koebner phenomenon, canities praecox, halo nevi, poliosis circumscripta), the number of pigmented lesions and the presence of autoantibodies are of significance in order to support (a) a subentity of childhood vitiligo and (b) whether there is a true predisposition or association of autoimmune or other diseases in this group of patients. The data confirm earlier results of a prevalence of thyroid disease and the presence of thyroid antibodies, whereas other diseases are a random event. 6.2% of the patients had congenital nevi compared with 2.8% in a normal healthy population. Based on the results of this study and the significant higher risk for development of melanomas in this patient group, an annual checkup is recommended.

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Alopecia Universalis, Onychodystrophy, and Total Vitiligo

Cited by 35 publications

References 13 publications

Coincidence of Vitiligo, Alopecia areata, Onychodystrophy, Localized Scleroderma and Lichen planus

Coincidence of Vitiligo, Alopecia areata, Onychodystrophy, Localized Scleroderma and Lichen planus

Vitiligo and Other Hypomelanoses of Hair and Skin

Vitiligo and Other Diseases: Coexistence or True Association?

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