Alopecia areata universalis in an infant

LaRow, Jo Anne; Mysliborski, Judith; Rappaport, Irving; Rouleau, Guy A.; Carlson, John A.

doi:10.1007/bf02737867

Cited by 6 publications

(6 citation statements)

References 26 publications

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“…Onychomadesis has been associated with alopecia areata. LaRow et al . published a case report of a 2‐year‐old child with alopecia areata universalis, and Tosti et al .…”

Section: Autoimmune Diseasementioning

confidence: 99%

Onychomadesis: literature review

Hardin

Haber

2015

Br J Dermatol

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Onychomadesis is characterized by separation of the nail plate from the matrix with persistent attachment to the nail bed and often, but not always, eventual shedding. Onychomadesis has been associated with infection, autoimmune disease, critical illness and medications. To our knowledge a literature review of all associations with onychomadesis has not been completed previously. Most commonly, onychomadesis has been reported in association with pemphigus vulgaris and hand-foot-mouth disease, and following chemotherapy or antiepileptic medications. This article summarizes these key culprit associations, postulates the pathogenesis of nail matrix arrest and summarizes the clinical outcomes. We conducted a retrospective review of cases of onychomadesis reported from January 1960 to March 2013. Using the PubMed database, the literature was searched using the following terms: 'onychomadesis' and 'proximal nail shedding'. Also, an Ovid search was carried out using the same terms. In total 56 articles have been published, including our previously reported series of idiopathic onychomadesis. Articles pertaining only to Beau's lines and not true onychomadesis were excluded. Onychomadesis has been associated with autoimmune disease, other major medical illness, neonatal illness, medication and infection.

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“…Onychomadesis has been associated with alopecia areata. LaRow et al . published a case report of a 2‐year‐old child with alopecia areata universalis, and Tosti et al .…”

Section: Autoimmune Diseasementioning

confidence: 99%

Onychomadesis: literature review

Hardin

Haber

2015

Br J Dermatol

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“…In the latter, the lesions are well‐circumscribed patches of loss of hair (alopecia) 2–6 . Alopecia universalis, a variant of AA, 7 is a rather unusual expression and has sparingly been reported in the English literature 1 . The presence of generalized hair loss therefore in infants is important, and should conform to the diagnosis of AU, 8 as in the current case.…”

mentioning

confidence: 58%

“…Early onset of AU invariably has a poor prognosis. In the previous case report of infantile AU, the hair was lost within 2 months of birth and never regrew 1 . PUVA has been reported to be an effective and safe treatment for AA.…”

mentioning

confidence: 87%

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Infant alopecia universalis: role of topical PUVA (psoralen ultraviolet A) radiation

Yoon

Kim

2005

Int J Dermatology

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“…A younger age of onset is believed to predict a poorer prognosis. Very few occurrences of AA in infants less than 6 months of age have been described in the Western literature (4–9).…”

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confidence: 99%