Alopecia areata and salmon patch: an actual association?

Nuchal nevus flammeus and alopecia areata: When size matters

“…Taking into consideration the results obtained, we agree with the previous studies[12349] and confirm that the prevalence of NNF is higher in patients diagnosed with AA. Moreover, we found not only a statistically significant association between AA and the presence of NNF but also with its size, which confirms our initial hypothesis.…”

“…Previous studies have suggested that the presence of a persistent nuchal nevus flammeus (NNF) also indicates a greater severity and duration of the disease. [1234]…”

“…NNF (also called NNF neonatorum, nuchal salmon patch, or nuchal nevus simplex) consists of congenital faint pink, blanchable patch with irregular borders located on the nape of the neck that becomes more visible during hard crying, fever, or temperature changes. [1567] There is evidence of a genetic influence in its etiology, and it seems to be inherited in an autosomal dominant manner. Contrary to those on the face which fade rapidly, nuchal lesions tend to be much more persistent and remain unchanged into adult life in at least 50% of cases.…”

“…in 1988,[2] who demonstrated that the relation was statistically evident and not due to a simple observer bias[8] (owing to the much more noticeable NNF in the naked occipital region, and the high prevalence of both NNF and AA), a theory that has been supported by further publications. [12349]…”