Alopecia areata

Pratt, C. Herbert; King, Lloyd E.; Messenger, Andrew G.; Christiano, Angela M.; Sundberg, John P.

doi:10.1038/nrdp.2017.11

Cited by 497 publications

(574 citation statements)

References 201 publications

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“…In our study, no associated cases of LE were observed, and only three comorbid cases of psoriasis were found. Other autoimmune disorders are less commonly reported in association with AA and are represented by Biermer disease, bowel inflammatory disorders, and celiac disease . AA is reported in 13% to 40% of cases of APECED syndrome .…”

Section: Discussionmentioning

confidence: 99%

Alopecia areata in Tunisia: epidemio‐clinical aspects and comorbid conditions. A prospective study of 204 cases

et al. 2019

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Background Alopecia areata (AA) is an autoimmune condition that usually presents as patchy, nonscarring hair loss. Autoimmune disorders and atopy are reported as comorbid conditions. We aimed to investigate the demographics, clinical characteristics, and associations of AA in Tunisian patients. Methods Demographic data, pattern of alopecia, age of onset, and associations were evaluated in 204 patients from January 2012 to June 2016. Results Two hundred and four cases of AA were seen. The male to female ratio was 0.68. The mean age at presentation was 23 years old. Positive family history was noticed in 22.1% of patients. Personal history of atopy was associated with AA in 18.1%. Associated autoimmune diseases were thyroid disorders (12.7%), vitiligo (1.5%), psoriasis (three cases), type 1 diabetes (two cases), autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED) syndrome (two cases), lichen sclerosus atrophicus (one case), and pemphigus vulgaris (one case). Patchy AA was the most common manifestation (49.5%) followed by alopecia universalis (27.5%), alopecia ophiasis (12.7%), and alopecia totalis (10.3%). Nail changes consisting of pitting, trachyonychia, and longitudinal ridging were reported in 24.8%. AA patterns were more severe in females (P = 0.049). Severe forms showed more persistent disease duration (P = 0.005), earlier onset (P = 0.001), and more recurring episodes (P = 0.002) and were significantly associated with nail involvement (P < 0.001). Conclusions Our study aimed to review epidemio‐clinical characteristics and comorbid conditions of AA in Tunisian patients. More severe cases with a pejorative value of early‐onset AA, long disease duration, and nail involvement were seen in our study.

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Section: Discussionmentioning

confidence: 99%

Alopecia areata in Tunisia: epidemio‐clinical aspects and comorbid conditions. A prospective study of 204 cases

et al. 2019

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“…1,20 For this reason, the diagnosis should be based on clinical history and physical examination. 34 The clinical history is one of the key elements to identify possible triggers of the disease or provides evidence to determine the presence of another clinical disorder. 2 The physical examination will allow to establish an accurate diagnosis, with the support of techniques like the hair pull test and the Jacquet's sign.…”

Section: Diagnosismentioning

confidence: 99%

Alopecia Areata. Current situation and perspectives

et al. 2017

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Alopecia areata (AA) is a dermatological disease characterized by non-scarring hair loss of the scalp and/or body, with an unpredictable and variable evolution in the patients in which, despite multidisciplinary efforts, its etiology is not entirely known, although some evidence suggests that environmental, immunological and genetic factors could be generating the disease. The aim of this review is to provide an updated panorama of the clinical characteristics, diagnosis and treatment of AA, to analyze the mechanisms that could participate in its etiology, as well as to review some of the most important genetic variants that could confer susceptibility to the development of this disease.

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“…It is also important to note that adult patients face higher risks of psychiatric diseases such as depression, anxiety, social phobia, and paranoid disorders (Pratt, King Jr, Messenger, Christiano, & Sundberg, 2017 …”

Section: Alopecia Areatamentioning

confidence: 99%

Trichopsychodermatology: The Psychiatric and Psychosocial Aspects of Hair Disorders

Jafferany

Patel

2019

Dermatologic Therapy

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Medical conditions involving hair are typically managed by a dermatologist. However, a significant psychosocial association has been found both in the development of hair conditions through primary pathologic involvement and as secondary comorbidity.Trichopsychodermatology is an emerging field aiming to better understand the psychiatric and psychosocial impacts of disorders involving hair. Trichotillomania or hairpulling disorder, alopecia areata, telegenic effluvium, anagen effluvium, and cicatricial alopecia represent common conditions within trichopsychodermatology. A lack in awareness, knowledge, and training of the field exists, which can act as a barrier for improving patient outcomes. This review provides a holistic understanding of specific psychotrichologic conditions that healthcare providers may encounter in order to facilitate the process of developing high-quality future therapeutic interventions.

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Alopecia areata

Cited by 497 publications

References 201 publications

Alopecia areata in Tunisia: epidemio‐clinical aspects and comorbid conditions. A prospective study of 204 cases

Alopecia areata in Tunisia: epidemio‐clinical aspects and comorbid conditions. A prospective study of 204 cases

Alopecia Areata. Current situation and perspectives

Trichopsychodermatology: The Psychiatric and Psychosocial Aspects of Hair Disorders

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