Aloe vera: From ancient knowledge to the patent and innovation landscape – A review

Martínez-Burgos, Walter José; Serra, Josilene Lima; MarsigliaF, Ronald M.; Montoya, Pedro; Vásquez, Zulma Sarmiento; Marín, Oranys; Gallego-Cartagena, Euler; Paternina-Arboleda, Carlos D.

doi:10.1016/j.sajb.2022.02.034

Cited by 23 publications

(13 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the literature, there are limited studies that have published the phytoconstituents of A. arborescens. Thus, most of the phytoconstituents detected in this study, such as xanthine, octanoic, indole and decanoic acid derivatives, have been previously identified from other Aloe species such as Aloe ferox and A. vera but not recorded from A. arborescens [ 32 , 33 , 34 ]. Therefore, the presence of these compounds implies that A. arborescens has potential pharmacological activities and can be considered in medical prophylactic and therapeutic schemes.…”

Section: Discussionmentioning

confidence: 69%

Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill

Maliehe

Nqotheni

Shandu

et al. 2023

Plants

View full text Add to dashboard Cite

Aloe arborescens Mill’s extracts have been explored for antibacterial and antioxidant efficacies. However, there is limited information on its chemical composition and mechanism of action. The purpose of this study was to assess the chemical composition, antibacterial and antioxidant activities and mechanism of the whole leaf extract of A. arborescens Mill. The phytochemical profile was analysed with gas chromatography mass spectrometry (GC-MS). The antioxidant and antibacterial activities were screened using 1,1diphenyl2picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and micro-dilution assays, respectively. The effects of the extract on the bacterial respiratory chain dehydrogenase, membrane integrity and permeability were analysed using iodonitrotetrazolium chloride, 260 absorbing materials and relative electrical conductivity assays. GC-MS spectrum revealed 26 compounds with N,N’-trimethyleneurea (10.56%), xanthine (8.57%) and 4-hexyl-1-(7-ethoxycarbonylheptyl)bicyclo[4.4.0]deca-2,5,7-triene (7.10%), being the major components. The extract also exhibited antioxidant activity with median concentration (IC50) values of 0.65 mg/mL on DPPH and 0.052 mg/mL on ABTS. The extract exhibited minimum inhibitory concentration (MIC) values ranging from 0.07 to 1.13 mg/mL. The extract inhibited the bacterial growth by destructing the activity of the respiratory chain dehydrogenase, membrane integrity and permeability. Therefore, the leaf extract has the potential to serve as a source of antibacterial and antioxidant compounds.

show abstract

Section: Discussionmentioning

confidence: 69%

Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill

Maliehe

Nqotheni

Shandu

et al. 2023

Plants

View full text Add to dashboard Cite

show abstract

“…has been meticulously documented throughout history ( Figure 2 ), with its earliest known utilization dating back to 1550 BC as evidenced in the “Ebers Papyrus”, an ancient Egyptian medical manuscript. 18 This ancient text notably underscores the medicinal applications of Aloe barbadensis Mill. during that era.…”

Section: The Historical and Traditional Use Of Aloe Barbade...mentioning

confidence: 96%

The Potential Application of Aloe Barbadensis Mill. as Chinese Medicine for Constipation: Mini-Review

Huang,

Fang,

et al. 2024

DDDT

View full text Add to dashboard Cite

Aloe barbadensis Mill. has a long history of medicinal use in the annals of traditional Chinese medicine, wherein it has garnered considerable renown. Its multifaceted therapeutic properties, characterized by its anti-inflammatory and antibacterial attributes, alongside its established efficacy as a laxative agent, have been extensively documented. This review commences with an exploration of the nomenclature, fundamental characteristics, and principal constituents of Aloe barbadensis Mill. responsible for its laxative effects. Subsequently, we delve into an extensive examination of the molecular mechanisms underlying Aloe barbadensis Mill.’s laxative properties, types of constipation treatments, commercially available preparations, considerations pertaining to toxicity, and its clinical applications. This review aims to serve as a comprehensive reference point for healthcare professionals and researchers, fostering an enhanced understanding of the optimal utilization of Aloe barbadensis Mill. in the treatment of constipation.

show abstract

“…It contains more than 75 biologically active components such as vitamins, minerals, monosaccharides, polysaccharides (glucomannan and acemannan), amino acids, anthraquinones, saponins, phytosterols, phenolic compounds and salicylic acids. The main phytonutrients are polysaccharides and anthraquinones [82]. The most important polysaccharide of aloe vera is acemannan, the degradation of which mainly occurs at temperatures between 200 and 600 °C In phase III (250-440 • C), weight losses were also high, varying from 28.4 to 36.8%.…”

Section: Thermogravimetric (Tga) Changes In Apple Tissuementioning

confidence: 99%

Effect of the Pulsed Electric Field Treatment on Physical, Chemical and Structural Changes of Vacuum Impregnated Apple Tissue in Aloe Vera Juices

Trusinska,

Drudi,

Rybak

et al. 2023

Foods

View full text Add to dashboard Cite

Vacuum impregnation (VI) stands as a diffusion-driven food processing method that has found recent application within the food industry, particularly for the cold formulation of fortified food products. Pulsed electric field (PEF) treatment can affect the food structure, influencing therefore the mass transfer phenomena during the further processing. Thus, the study aimed at investigating the effect of PEF treatment on selected physicochemical properties of vacuum-impregnated apples. Apple slices were vacuum impregnated with aloe vera juice solution with or PEF treatment at different intensities (125, 212.5 or 300 V/cm). The PEF was applied as a pretreatment—applied before the VI process as well as posttreatment—applied after the VI process. The VI process with aloe vera juice resulted in a sample weight increase of over 24% as well as structural changes, partial cell viability loss and color alteration. In addition, the decrease of bioactive compounds was observed, while antioxidant activity remained at a similar level as in raw material. PEF treatment adversely affected vacuum impregnation efficiency, causing microstructural changes and cell viability loss. Additionally, chemical composition modifications were evident through thermogravimetric analysis (TGA) and Fourier Infrared Spectroscopy (FTIR) analyses. Tissue hardness decreased significantly due to structural damage and caused high leakage from plant tissue, which resulted in hindering saturation with aloe vera juice during the VI process. Additionally, reduced bioactive substance content after PEF treatment was observed and the VI process did not restore apple samples of the bioactive compounds from aloe vera juice.

show abstract

Aloe vera: From ancient knowledge to the patent and innovation landscape – A review

Cited by 23 publications

References 79 publications

Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill

Chemical Profile, Antioxidant and Antibacterial Activities, Mechanisms of Action of the Leaf Extract of Aloe arborescens Mill

The Potential Application of Aloe Barbadensis Mill. as Chinese Medicine for Constipation: Mini-Review

Effect of the Pulsed Electric Field Treatment on Physical, Chemical and Structural Changes of Vacuum Impregnated Apple Tissue in Aloe Vera Juices

Contact Info

Product

Resources

About