2022
DOI: 10.1590/s2175-97902022e20837
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Aloe vera and wound healing: a brief review

Abstract: The mechanism underlying the healing process involves cellular, subcellular, physiological, and biochemical events which act together to repair injuries

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Cited by 8 publications
(7 citation statements)
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“…A. vera is composed mainly of polysaccharides, proteins, minerals, and water [112]. Traditionally, the leaf gel of A. vera has been used to treat wounds and other skin problems; its wound-healing properties are attributed to acemannan and glucomannan (Figure 3), two polysaccharides produced in the leaf gel [112,113]. Although A. vera gel is used extensively for treating dermal wounds, few studies have assessed this effect on corneal injury, and the molecular mechanisms underlying this beneficial effect are associated with the re-epithelialization process (Figure 4).…”
Section: Pharmacological Efficacy and Safety Studiesmentioning
confidence: 99%
“…A. vera is composed mainly of polysaccharides, proteins, minerals, and water [112]. Traditionally, the leaf gel of A. vera has been used to treat wounds and other skin problems; its wound-healing properties are attributed to acemannan and glucomannan (Figure 3), two polysaccharides produced in the leaf gel [112,113]. Although A. vera gel is used extensively for treating dermal wounds, few studies have assessed this effect on corneal injury, and the molecular mechanisms underlying this beneficial effect are associated with the re-epithelialization process (Figure 4).…”
Section: Pharmacological Efficacy and Safety Studiesmentioning
confidence: 99%
“…A. vera has been utilized in different DDSs, e.g. , emulgel, 20 sustained release oral hydrogel disc, 21 nanoparticles, 22 buccal, oral, and transdermal gels, 23 wound dressing, 24,25 etc.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, Aloe vera is the most common Aloe variety distributed around the world. This perennial succulent xerophyte herb has several medicinal and pharmacological benefits for human health, such as skin care characteristics, immune modulation, anticancer, and gastroprotective properties, as well as wound healing properties (Hamman, et al, 2008;Lucini et al, 2015;Massoud et al, 2022). The Jordanian Ministry of Agriculture (MOA) encourages local framers to increase cultivation of this plant due to its medicinal and health benefits and its ability to grow in a dry condition, given recent challenges with water shortage and climate change in the country.…”
Section: Introductionmentioning
confidence: 99%