Allylic Hydroxy Phosphonates: Versatile Chiral Building Blocks.

Abstract

Organo-phosphorus compounds S 0080Allylic Hydroxy Phosphonates: Versatile Chiral Building Blocks. -Palladium--catalyzed reactions of allylic hydroxy phosphonates, e.g. (I), with nitrogen nucleophiles represents an efficient regio-and stereoselective pathway to βand γ-substituted amino phosphonates, e.g. (III) and (IV). In a similar manner, the rearrangement of allylic tosyl carbamates like (V) proceeds in a stereoselective manner (16th international conference on phosphorus chemistry). -(DE LA CRUZ, A.; HE, A.; THANAVARO, A.; YAN, B.; SPILLING*, C. D.; RATH, N. P.; J. Organomet. Chem. 690 (2005) 10, 2577-2592; Dep. Chem. Biochem., Univ. Mo., St. Louis, MO 63121, USA; Eng.) -Mischke 42-192