Ally, adversary, or arbitrator? The context-dependent role of eosinophils in vaccination for respiratory viruses and subsequent breakthrough infections
Lauren A Chang,
Michael Schotsaert
Abstract:Eosinophils are a critical type of immune cell and central players in Type 2 immunity. Existing literature suggests that eosinophils also can play a role in host antiviral responses, typically Type 1 immune events, against multiple respiratory viruses, both directly through release of antiviral mediators and indirectly through activation of other effector cell types. One way to prime host immune responses towards effective antiviral responses is through vaccination, where typically a Type 1-skewed immunity is … Show more
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