Abstract:Background During status epilepticus, severe seizures can occur, generating recurrent cycles of excitotoxicity and oxidative stress that cause neuronal damage and cell death. The administration of agents with antioxidant properties represents a therapeutic alternative aimed at reducing the severity of status epilepticus and mitigating the neurobiological consequences that precede them.Objective The objective of this work was to evaluate the antiseizure effect of the antioxidants allopurinol (ALL) and ellagic a… Show more
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