Alloprocoptic selection: A mode of natural selection promoting polymorphism

Serradilla, J. M.; Ayala, Francisco J.

doi:10.1073/pnas.80.7.2022

Cited by 21 publications

(7 citation statements)

References 20 publications

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“…Data consistent with this hypothesis come from a study of patterns of mating and fecundity of Drosophila melanogaster (Serradilla & Ayala, 1983). Heterozygotes for the aglycerophosphate locus, the alcohol dehydrogenase locus, and the acid phosphatase locus produced approximately 50% more eggs than homozygotes.…”

Section: Enzymes Directly Influence Developmental Homeostasismentioning

confidence: 51%

Enzyme heterozygosity, metabolism, and developmental stability

Mitton

1993

Genetica

119

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Developmental homeostasis, measured as either fluctuating asymmetry or variance of morphological characters, increases with enzyme heterozygosity in many, but not all, natural populations. These results have been reported for Drosophila, monarch butterflies, honeybees, blue mussels, side-blotched lizards, killifish, salmonid fishes, guppies, Sonoran topminnows, herring, rufous-collared sparrows, house sparrows, brown hares, white-tailed deer, and humans. Because heterozygosity at a few loci can not predict heterozygosity of the entiry genome, these loci must be detecting localized zones that influence the developmental environment.Studies of malate dehydrogenase in honeybees, Apis mellifera, and lactate dehydrogenase in killifish, Fundulus heteroclitus, revealed that developmental homeostasis varied with heterozygosity of individual loci. Heterozygotes differed from homozygotes in fluctuating asymmetry, morphological variance, and in correlations between morphological characters.The protein loci in these studies code for enzymes, and therefore do not directly influence morphological characters. However, some enzymatic loci substantially influence metabolism, and contribute to variation in the amount of energy available for development and growth. This argument can be made most convincingly for the LDH polymorphism in killifish. LDH genotypes differ in enzyme kinetic properties that measure differences in physiological efficiency, and these differences produce measurable and predictable differences in physiology and development. Under environmental conditions which impose a stress upon development, genotypes at these loci may have different amounts of energy available for development, and consequently exhibit different levels of developmental homeostasis.

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Section: Enzymes Directly Influence Developmental Homeostasismentioning

confidence: 51%

Enzyme heterozygosity, metabolism, and developmental stability

Mitton

1993

Genetica

119

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“…The departures from expectation for thesc combinations are highlighted in italics in "fable 11. The evolutionary significance of this pattern of interactions is that it will contribute to maintaining genetic polymorphism (Serradilla & Ayala, 1983;Hadeler & Liberman, 1975;Cockeram et al, 1972). Figure 1 summarizes the fecundity data.…”

Section: Resultsmentioning

confidence: 99%

“…A more distinctive phenomenon is that matings between dissimilar homozygotes have greater fecundity than matings between like homozygotes. This mode of selection in which association of opposites increases their fitness has been named alloprocoptic selection (Serradilla & Ayala, 1983). How large a role it may play in preserving allozymc and other polymorphisms must wait further investigation.…”

Section: Discussionmentioning

confidence: 99%

Effects of allozyme variation on fitness components in Drosophila melanogaster

Serradilla

Ayala

1983

Genetica

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We have explored in Drosophila melanogaster the fitness effccts of allelic variation at three enzyme loci: aGdh, Adh, and Acph. Viability and rate of development are studied at two densities, near-optimal and competitive. No genotypic effects could be demonstrated on rate of development at either density or on viability under optimal conditions. Small but significant effects on viability appear under competitive conditions. Fecundity is measured for all ninc possible mating combinations between the three female and thc three male genotypes at each locus. Female genotype has important fitness consequences; heterosis exists at every locus. Male genotype also contributes to fitness, but without heterosis. There are significant interactions between female and male genotypes, so that the fecundity of a mating combination cannot be determined from the average fitnesses of the female genotype and the male genotype involved.

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“…Fecundity as a fitness component is usually considered only in terms of the female, although it may also be affected by the presence of males. For example, Serradilla and Ayala (1983) kept different female and male genotypes in vials and found that fecundity depended on the male as well as the female genotype. Theoretical work (Hadeler and Liberman, 1975) indicates that such interactions between the sexes can give rise to stable equilibria for genetic polymorphisms not predicted by independent fertility estimates for the sexes.…”

mentioning

confidence: 99%