Allografts versus Equine Xenografts in Calcaneal Fracture Repair

Sönmez, Mehmet Mesut; Armağan, Raffi; Uğurlar, Meriç; Eren, Tugrul

doi:10.1053/j.jfas.2017.01.015

Cited by 12 publications

(17 citation statements)

References 30 publications

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“…Another aspect to be considered in the choice of bone graft is the cost. As shown in several studies, another argument for xenogeneic bone grafts is that they are less expensive than allogeneic grafts [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Individual Concepts in Foot Surgery: A Comparison of Xenogeneic and Autologous Bone Grafts Used in Adults for Lateral Calcaneus-Lengthening Osteotomy According to Evans

Siegel¹,

Bode²,

Brandenburg

et al. 2022

JPM

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Background: Xenogeneic bone grafts, when compared to autologous grafts, are supposed to provide structural benefits without donor site morbidity. To date, there have been divergent results in the use of xenogeneic grafts in foot surgery, primarily in pediatric patient cohorts. The present study examines the incorporation and maintenance of the achieved correction using autologous and xenogeneic bone grafts in adult patients with a six-month follow-up period. Material/Methods: In this retrospective study, 31 adult patients (43 feet in total) treated in our clinic by a lateral calcaneus-lengthening osteotomy, according to Evans, between 01/2006 and 12/2020 were included. The patients were assigned to study groups according to the use of xenogeneic or autologous bone grafts. The osseous incorporation following the criteria of Worth et al., correction maintenance by measuring the talo-navicular coverage angle (TNCA), the talo-first metatarsal angle (TFMA), the calcaneal pitch angle (PCA) and necessary revisions six months after surgery were extracted from the medical files retrospectively. Furthermore, the medical files were screened for the relevant comorbidities, nicotine abuse, BMI, sex and age. Results: In total, 27 autogenous (iliac crest) and 16 xenogeneic bone grafts of bovine origin were used. The evaluation of the radiographs at follow-up demonstrated that there was a mean incorporation rate of 96.3% for the autologous grafts and 57% for the patients treated with xenogeneic grafts (p = 0.002). Compared to the autologous group, xenogeneic grafts did not increase the loss of hindfoot alignment in the postoperative course, regardless of being incorporated or not. ΔTNCA, ΔTFMA and ΔPCA displayed no significant differences in both groups (p = 0.45, p = 0.42 and p = 0.10). Conclusion: Despite a significantly lower incorporation rate, the use of xenogeneic grafts was not accompanied with a greater risk of hindfoot alignment loss in the first six months after surgery. Early revision after a postoperative course of six months should not be motivated solely by the radiographic picture of incomplete osseous integration.

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Section: Discussionmentioning

confidence: 99%

Individual Concepts in Foot Surgery: A Comparison of Xenogeneic and Autologous Bone Grafts Used in Adults for Lateral Calcaneus-Lengthening Osteotomy According to Evans

Siegel¹,

Bode²,

Brandenburg

et al. 2022

JPM

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“…Autograft merupakan graft yang diambil dari bagian tubuh pasien itu sendiri, allograft marupakan graft yang diambil dari manusia lain (same species), sedangkan xenograft merupakan graft yang diambil dari spesies mamalia. Berbagai jenis bone graft tersebut memiliki kelemahan, diantaranya risiko terjadinya infeksi, berpotensi merusak kesehatan jaringan tulang, biaya yang mahal, membutuhkan prosedur medis yang rumit (Puska, Aho, & Vallittu, 2011) serta berpotensi menyebabkan komplikasi dari donor (Sonmez, Armagan, Ugurlar, & Eren, 2017). Sehingga diperlukan alternatif untuk menangani kelemahan tersebut, salah satunya adalah penggunaan bone graft yang terbuat dari material buatan (sintetis) (Van Lieshout, Van Kralingen, El-Massoudi, Weinans, & Patka, 2011).…”

Section: Pendahuluanunclassified

Parameter Optimization of Customized FDM 3D Printer Machine for Biocomposite Material [Sago/PMMA] Using 2k Fractional Factorial Design

Rosid

Tontowi

2021

Jurnal Optimasi Sistem Industri

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Bone fracture caused by various incident causes medical problems. Then bone restoration is required. Bone grafts can be used to solve this problem. One of the materials that can be used to produce bone graft is PMMA. PMMA requires to be combined with other materials to extend the solidification time. The material that can be used for bone graft material is sago starch. The main ingredient composition of Biocomposite [sago/PMMA] consists of sago: PMMA = 1 : 1 (w/w). The composition of the addition of MMA is 10% (v/w) of PMMA, this is to extend the curing time. Thus the material can be through from the chamber extruder to the nozzle. This research aims to obtain combinations of 3D Printer FDM Customized machine parameters for minimizing of error dimension. The 3D Printer machine uses pneumatic system to push the material from the container to the chamber and used screw extruder to push the material out through the nozzle. The experimental design method used a 2 k fractional factorial design, with 3 parameters, 2 levels and 3 responses. The experimental results obtained that the layer height parameter has a significant influence on the x-dimensional error. The optimization results obtained a combination of parameters to get the smallest error dimensions, the print speed is 25 mm/s, the layer height is 2.93 mm and the fill density is 20%. The results of optimization obtained that the x-dimensional error is 0.016, the ydimensional error is 0.069 and the z-dimensional error is 0.4539.

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“…Successful ARP outcomes were recently achieved by grafting the post-extraction socket with enzyme-deantigenic equine bone (EDEB), which also consists of a mixture of cancellous and cortical bone granules (diameter 0.25-1 mm) made non-antigenic with digestive enzymes [37,38]. In addition to ARP procedures, EDEB was used with satisfactory results in peri-apical cyst-removal management [39], horizontal/vertical ridge and sinus augmentation [40][41][42], and orthopedic applications [43][44][45].…”

Section: Introductionmentioning

confidence: 99%

A comparison between anorganic bone and collagen-preserving bone xenografts for alveolar ridge preservation: systematic review and future perspectives

Stefano

Orlando

Ottobelli³

et al. 2022

Maxillofac Plast Reconstr Surg

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After tooth extraction, dimensional changes affect the alveolar socket, leading to loss in alveolar bone height and width. Histological modifications also occur, with initial formation of a blood clot that is replaced with granulation tissue and subsequently with a provisional connective tissue matrix. Spontaneous healing ends with socket filling with woven bone, which is gradually replaced with lamellar bone and bone marrow. Adequate alveolar ridge dimensions and bone quality are required to assure optimal stability and osseointegration following dental implant placement. When a tooth is extracted, alveolar ridge preservation (ARP) procedures are an effective method to prevent collapse of the post-extraction socket. Heterologous bone is widely chosen by clinicians for ARP, and anorganic bone xenografts (ABXs) made bioinert by heat treatment represents the most used biomaterial in clinical applications. Collagen-preserving bone xenografts (CBXs) made of porcine or equine bone are fabricated by less invasive chemical or enzymatic treatments to remove xenogenic antigens, and these are also effective in preserving post-extraction sites. Clinical differences between anorganic bone substitutes and collagen-preserving materials are not well documented in the literature but understanding these differences could clarify how processing protocols influence biomaterial behavior in situ. This systematic review of the literature compares the dimensional changes and histological features of ABXs versus CBXs in ridge preservation procedures to promote awareness of different bone xenograft efficacies in stimulating the healing of post-extraction sockets.

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Allografts versus Equine Xenografts in Calcaneal Fracture Repair

Cited by 12 publications

References 30 publications

Individual Concepts in Foot Surgery: A Comparison of Xenogeneic and Autologous Bone Grafts Used in Adults for Lateral Calcaneus-Lengthening Osteotomy According to Evans

Individual Concepts in Foot Surgery: A Comparison of Xenogeneic and Autologous Bone Grafts Used in Adults for Lateral Calcaneus-Lengthening Osteotomy According to Evans

Parameter Optimization of Customized FDM 3D Printer Machine for Biocomposite Material [Sago/PMMA] Using 2k Fractional Factorial Design

A comparison between anorganic bone and collagen-preserving bone xenografts for alveolar ridge preservation: systematic review and future perspectives

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