Allograft vs. exposure in the treatment of scalds—a prospective randomized controlled clinical study

A general overview of burn care

“…A number of different temporary cover materials is available: the most common ones are allografts (cadaver skin from a skin bank, amnion membrane) (95–105), xenografts [primarily porcine skin (106,107), less commonly used nowadays] or (semi) synthetic materials. One of the semisynthetic materials is bilayered and designed in such a way that the wound bed grows into the wound side layer of the material: it thus becomes a ‘neodermis’(108–111).…”

“…A number of different temporary cover materials is available: the most common ones are allografts (cadaver skin from a skin bank, amnion membrane) (95)(96)(97)(98)(99)(100)(101)(102)(103)(104)(105), xenografts [primarily porcine skin (106,107), less commonly . when the depth of a burn is difficult to determine, tangenitial excision can be used as a diagnostic tool .…”

Biologic wound coverings in burn treatment

“…In spite of reports of permanent success in the early years of homografting, it was soon concluded that permanent take was impossible with homografts. In 1926 it was proposed that the immunological system of the recipient was responsible for the fate of the homograft tissue [13] and that suppression of the recipient's immune system was one of the routes available for achieving a permanent take [14].…”