Allogeneic Hematopoietic Stem Cell Transplantation, Especially Haploidentical, May Improve Long-Term Survival for Children with High-Risk T-Cell Acute Lymphoblastic Leukemia in First Complete Remission
Abstract:Background: The role of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for children with high-risk (HR) T- cell acute lymphoblastic leukemia (T-ALL) in first complete remission (CR1) is still under critical discussion. Moreover, relapse is still the main factor affecting survival. This study explored the effect of allo-HSCT (especially haploidentical HSCT (haplo-HSCT) ) on improving survival and reducing relapse for children with HR T-ALL in CR1 and the prognostic factors of childhood T-ALL in … Show more
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