Allergy Testing — An Overview

Gupta, Neeraj; Agarwal, Poojan; Sachdev, Anil; Gupta, Dhiren

doi:10.1007/s13312-019-1652-x

Cited by 16 publications

(23 citation statements)

References 22 publications

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“…95 The PPT is widely used in human allergology to test for allergic rhinitis, eczema, asthma and food allergy. 96,97 In small animal dermatology, very few studies have assessed the usefulness of PPT in dogs 98,99 and cats 93,100 with environmental allergies. In dogs, the first study 99 comparing IDT and PPT showed that IDT was much easier to interpret than PPT, and thus for more than two decades the PPT was abandoned.…”

Section: Intradermal Testingmentioning

confidence: 99%

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Clinical signs and diagnosis of feline atopic syndrome: detailed guidelines for a correct diagnosis

Santoro

Pucheu‐Haston

Prost

et al. 2021

Veterinary Dermatology

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Background-Feline atopic syndrome (FAS) describes a spectrum of hypersensitivity disorders characterised by highly diverse clinical presentations including skin, gastrointestinal and respiratory systems. Among these disorders is feline atopic skin syndrome (FASS), in which hypersensitivity is typically associated with environmental allergens, although food allergy may coexist. Involvement of other organ systems (e.g. asthma) also may occur. Because of its highly heterogeneous clinical presentation, diagnosis of FASS can be challenging. Objectives-A subgroup of the International Committee on Allergic Diseases of Animals was tasked to summarise the most current information on the clinical presentations of FASS and to develop diagnostic guidelines. Methods and materials-Online citation databases and abstracts from international meetings were searched for publications related to feline allergic conditions. These were combined with expert opinion where necessary. Results-A total of 107 publications relevant to this review were identified. Compilation of these data enabled development of a detailed description of the clinical features of FASS and development of guidelines focusing on systematic elimination of other skin conditions with similar clinical characteristics. As allergen tests are frequently used by dermatologists to support a clinical diagnosis of FASS, a brief review of these methodologies was also performed. Conclusions and clinical importance-In a similar way to atopic dermatitis in dogs, FASS is a clinical diagnosis based on the presence of compatible clinical signs and exclusion of other diseases with similar clinical features. Elimination or exclusion of fleas/flea allergy, other parasites, infections and food allergy is mandatory before reaching a diagnosis of FASS.

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Section: Intradermal Testingmentioning

confidence: 99%

“…This method is associated with very low risk of adverse reactions 95 . The PPT is widely used in human allergology to test for allergic rhinitis, eczema, asthma and food allergy 96,97 …”

Section: Diagnosis Of Fassmentioning

confidence: 99%

Clinical signs and diagnosis of feline atopic syndrome: detailed guidelines for a correct diagnosis

Santoro

Pucheu‐Haston

Prost

et al. 2021

Veterinary Dermatology

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“…A positive reaction was defined as a wheal with a diameter >3 mm after subtracting the negative control. 21 …”

Section: Methodsmentioning

confidence: 99%

Prevalence and risk factors of allergic rhinitis and asthma in the southern edge of the plateau grassland region of northern China: A cross-sectional study

Chen

Pang

et al. 2021

World Allergy Organization Journal

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Background The prevalence rates of allergic rhinitis (AR) and asthma in the border region of China may be different from those in the central region of plateau grasslands. A survey was performed to investigate the prevalence and risk factors for AR, asthma, and AR combined with asthma among adults (age ≥ 20 years) residing in the southern border of plateau grasslands in northern China. Methods From May to August 2018, a cross-sectional survey was completed by subjects that were selected using a cluster random sampling method. The subjects completed a questionnaire and were administered skin prick tests (SPTs). Risk factors for AR, asthma, and AR combined with asthma were examined by multivariate logistic regression analyses. Results A total of 1815 adult subjects in the selected region completed study. The prevalence rates of physician-diagnosed AR, asthma, and AR combined with asthma were 13.9% (253), 9.8% (177), and 2.9% (52), respectively. Among the patients with AR, 20.6% were found to have concurrent asthma; among the patients with asthma, 29.4% were found to have concurrent AR. Artemisia and Humulus pollen were the most common sensitizing pollen types. Approximately 70% of subjects with AR and <30% of asthma patients were sensitized to Artemisia and Humulus pollen. Symptoms of AR and asthma mainly appeared during August. A multivariable logistic regression analysis identified sensitization pollen as an independent risk factor for both AR and AR combined with asthma (AR: OR = 16.23, 95% CI: 10.15–25.96; AR combined with asthma: OR = 6.16, 95% CI: 1.28–29.66). An age >40 years old, family history of asthma, moderate-to-severe AR, adverse food reactions, and mold allergies were independent risk factors for AR combined with asthma. Conclusions This study identified the prevalence rates of AR and asthma in the southern borders of the plateau grassland in northern China (>1500 m above sea level). Sensitization pollen is an independent risk factor for AR and AR combined with asthma.

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“…Major limitation of the test is difficulty in interpretation, especially for subjective symptoms. 760 716 Serum IgE levels varies with age. Initially, serum IgE levels increase progressively up to the age of 15 years, than decline from the 2nd to the 8th decade of life.…”

Section: Food Allergen Provocation Testmentioning

confidence: 99%