Allergy of anaesthetizing agents in Spain

Tamayo, Eduardo; Pérez, Miguel Ángel Rodríguez; Gomez, J. I. Esquivias; Álvarez, F. Javier

doi:10.1093/bja/83.2.336

Cited by 10 publications

(4 citation statements)

References 4 publications

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“…Various scenarios can occur in clinical practice: i) patients have no previous clinical history of perioperative allergic reaction. In these cases there is no indication of performing STs (grade of recommendation, B) [12,118,128] ii) patients with a previous history of reactions, with detailed information available regarding the reaction kinetics and drugs and agents administered. In these cases, STs are mandatory for all the agents administered plus latex [129] and clorhexidine [71,103,104,130] (grade of recommendation, C), however ST results may not be reliable until 4-6 weeks after the initial reaction [131]; iii) Patients with reactions but without clear information about the episode, which is the most complex scenario, especially when there is a long interval between the reaction and the study.…”

Section: Skin Testsmentioning

confidence: 99%

Practical Guidelines for Perioperative Hypersensitivity Reactions

Laguna¹,

Archilla²,

Doña³

et al. 2018

J Investig Allergol Clin Immunol

105

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Perioperative hypersensitivity reactions constitute a first-line problem for anesthesiologists and allergists, so it is advisable that hospitals have a consensus protocol for the diagnosis and management of these reactions. However, this kind of protocols is not present in many hospitals, leading to problems in treatment, the communication of incidents and subsequent etiological diagnosis. In this document we present a systematic review of the available scientific evidence and provide general guidelines for the management of acute episodes and Resumen:Las reacciones de hipersensibilidad perioperatorias constituyen un problema de primera línea para los anestesiólogos y alergólogos, por lo que es recomendable que los hospitales tengan un protocolo de consenso para el diagnóstico y el tratamiento de estas reacciones. Sin embargo, este tipo de protocolos no está presente en muchos hospitales, lo que conlleva problemas en el tratamiento, la comunicación de incidentes y el posterior diagnóstico etiológico. Este documento ha sido creado por miembros del Comité de Alergia a Medicamentos de la Sociedad Española de Alergia e Inmunología Clínica (SEAIC) en colaboración con miembros de la Sociedad Española de Anestesia (SEDAR). Se ha realizado una revisión sistemática de la evidencia científica disponible y se proporcionan pautas generales para el manejo de episodios agudos y para la derivación de pacientes con reacciones de hipersensibilidad perioperatoria a los Servicios de Alergología. Se propone un algoritmo práctico para el diagnóstico etiológico y se brindan recomendaciones para el manejo de pacientes con reacciones alérgicas perioperatorias.

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Section: Skin Testsmentioning

confidence: 99%

Practical Guidelines for Perioperative Hypersensitivity Reactions

Laguna¹,

Archilla²,

Doña³

et al. 2018

J Investig Allergol Clin Immunol

105

View full text Add to dashboard Cite

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“…Allergic reactions occurring during anaesthesia are always a concern for anaesthesiologists in all countries, because of the clinical repercussions as well as the medical–legal implications (1, 2). In Spain, in 1993, the High Court found an anaesthesiologist guilty for failing to carry out allergy tests on a patient who was about to undergo surgical intervention under general anaesthetic, and who subsequently suffered a serious allergic accident (2). Since then, many anaesthesiologists have begun to demand that allergy tests are performed for all substances used in surgical interventions, resulting in the collapse of allergy units.…”

Section: Prevalence Of Patients With Positive Prick Test and Agents mentioning

confidence: 99%

“…Since then, many anaesthesiologists have begun to demand that allergy tests are performed for all substances used in surgical interventions, resulting in the collapse of allergy units. Allergy tests on anaesthetizing are indicated only among those patients who have a history of an adverse reaction to these; this is the case, in fact, with other drugs (2, 3). However, no information is available regarding prevalence of prick tests among the surgical population without the criteria mentioned.…”

Section: Prevalence Of Patients With Positive Prick Test and Agents mentioning

confidence: 99%

Prevalence of positive prick test to anaesthetic drugs in the surgical population

Tamayo

Álvarez

Rodríguez-Ceron

et al. 2006

Allergy

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“…Allergic reactions occurring during anesthesia are always a concern for anesthesiologists in all countries because of the clinical repercussions, as well as the medical and legal implications [1,2]. In addition, many people who claim to have experienced a drug hypersensitivity reaction are categorized as allergic, with no further investigation [3,4].…”

Section: Introductionmentioning

confidence: 99%

Self‐reported drug allergies and the diagnostic work‐up in the surgical population

Tamayo

Álvarez

Castrodeza

et al. 2010

Evaluation Clinical Practice

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Objective The diagnostic work-up of a drug hypersensitivity reaction is indeed difficult. In general, medical documentation of allergic reactions in medical reports is usually highly deficient or non-existent. The aim of this study was to analyse the prevalence of selfreported drug allergies in the surgical population as well as the criteria used in the diagnosis of drug hypersensitivity reactions. Methods A prospective study with the consecutive participation of 1439 patients, following surgical intervention, attended the Post-Operative Care Unit. Previously, as a routine process during the pre-anesthesia consultation, all patients were questioned about whether they had any drug allergies to report and diagnostic work-up. Results The prevalence of self-reported drug allergies was 8.3% (119/1439): 3.6% considered themselves allergic to b-lactams and 2.4% to non-steroidal anti-inflammatory drugs. Approximately one-third of the subjects (40 out of the 119) had not been subjected to any allergy diagnostic procedure and with 79 (66.4%), the only diagnostic test used by the Allergy Unit had been the skin prick-test. None of those participating in the study had tryptase, methylhistamine, specific IgE or intradermal tests carried out to characterize the diagnosis of the allergic reaction. Conclusions These results show that self-reported drug allergies are highly prevalent and as yet little explored. It is an important prevalence which should bring about modifications to the prescription of certain medicaments. The medical personnel must be made aware of the need to make an accurate diagnosis of allergies to medicaments.

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Allergy of anaesthetizing agents in Spain

Cited by 10 publications

References 4 publications

Practical Guidelines for Perioperative Hypersensitivity Reactions

Practical Guidelines for Perioperative Hypersensitivity Reactions

Prevalence of positive prick test to anaesthetic drugs in the surgical population

Self‐reported drug allergies and the diagnostic work‐up in the surgical population

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