Abstract:Background Type I and type IV hypersensitivity can play an important role in phlebology with potential severe consequences for patients and treatment results.
Methods A review of literature was performed for allergic reactions in patients treated for venous insufficiency and venous leg ulcers (VLU), together with a study in the Dutch and European centre for adverse drug reactions. Besides, we performed a survey among 37 Dutch medical hospitals to investigate the incidence of treatment allergies.
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