Allergic rhinitis: Selective comparisons of the pharmaceutical options for management

Abstract

The depth and variety of pharmaceuticals available to manage the syndrome of allergic rhinitis is unparalleled. To arrive at a personal formulary, a physician would be well advised to understand what patients want and what they are willing to accept in terms of expense and adverse events. Patients want medications that are nonsteroidal, non habituating, produce no drowsiness, and could be used intermittently on demand only. This review is intended as an aid in comparing classes and formats of medications affecting nasal allergy.

Does the reduction of inferior turbinate affect lower airway functions?

“…3 Many different conservative ITH therapies have been applied, including the use of antihistamines, systemic decongestants, or intranasal sprays. 4 , 5 However, surgical reduction may be a good option in those cases in which medical treatment has failed, and it is the most effective treatment for ITH. 6 Radiofrequency Ablation (RFA) is widely used for the surgical reduction of inferior turbinate's, although there is a lack of consensus regarding the optimal surgical technique.…”

“…Even though the nose and lungs are usually treated as separate entities, the upper and lower airways can be regarded as a single anatomical and functional unit, since they directly affect each other. 4 The treatment of sinonasal pathologies, including allergic rhinitis, sinusitis, nasal polyps, and septal deviation, helps to resolve not only nasal obstruction, but can also positively influence lower airway functions. 10 , 11 , 12 , 13 For this research, we aimed to evaluate the effects of the treatment of persistent ITH on nasal and pulmonary functions.…”

Intranasal Spray Medications for Maintenance Therapy of Allergic Rhinitis

“…Ideally, many patients would prefer treatment that could be used when needed (i.e., when symptomatic). [4][5][6]9,10,16,55 Intranasal sprays may be evolving to meet these needs. In addition, using a simple disease control assessment tool, such as the Rhinitis Control Assessment Test, may give patients a better idea of what good control means, and, by doing so, help to motivate patients to better adhere to therapy and self-management routines.…”

Turbidimetric carbamazepine immunoassay on the ADVIA® 1650 and 2400 analyzers is free from interference of antihistamine drugs hydroxyzine and cetirizine

“…Hydroxyzine is a commonly prescribed first-generation antihistamine with sedative properties and has a benzhydrylpiperazine structure. Hydroxyzine is also one of the drugs used in the first-line therapy for the treatment of allergic rhinitis and chronic idiopathic urticaria (1,2). This drug is also used in the treatment of generalized anxiety disorder (3).…”