Allergic rhinitis is associated with poor asthma control in children with asthma

Groot, Eric P. de; Nijkamp, Anke; Duiverman, Eric J.; Brand, Paul

doi:10.1136/thoraxjnl-2011-201168

Cited by 178 publications

(160 citation statements)

References 35 publications

(32 reference statements)

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“…Incomplete asthma control in children was significantly more likely in children with AR than in those without. 36 Rhinitis was more frequent when control of asthma was worse. 37 Both retrospective and prospective claims data show that treating AR reduces asthma-related hospitalizations and emergency room visits by about half.…”

Section: Ar Control Impacts Asthma Controlmentioning

confidence: 99%

Underdiagnosed and Undertreated Allergic Rhinitis in Urban School-Aged Children with Asthma

Esteban

Klein

Kopel

et al. 2014

Pediatric Allergy, Immunology, and Pulmonology

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Allergic rhinitis (AR) is a risk factor for the development of asthma, and if poorly controlled, it may exacerbate asthma. We sought to describe AR symptoms and treatment in a larger study about asthma, sleep, and school performance. We examined the proportion (1) who met criteria for AR in an urban sample of school children with persistent asthma symptoms, (2) whose caregivers stated that they were not told of their child's allergies, (3) who had AR but were not treated or were undertreated for the disease, as well as (4) caregivers and healthcare providers' perceptions of the child's allergy status compared with study assessment, and (5) associations between self-report of asthma and AR control over a 4-week monitoring period. One hundred sixty-six children with persistent asthma participated in a clinical evaluation of asthma and rhinitis, including allergy testing. Self-report of asthma control and rhinitis control using the Childhood Asthma Control Test (C-ACT) and Rhinitis Control Assessment Test (RCAT) were measured 1 month after the study clinic session. Persistent rhinitis symptoms were reported by 72% of participants; 54% of rhinitis symptoms were moderate in severity, though only 33% of the sample received adequate treatment. AR was newly diagnosed for 53% during the clinic evaluation. Only 15% reported using intranasal steroids. Participants with poorly controlled AR had poorer asthma control compared with those with well-controlled AR. This sample of urban school-aged children with persistent asthma had underdiagnosed and undertreated AR. Healthcare providers and caregivers in urban settings need additional education about the role of allergies in asthma, recognition of AR symptoms, and AR's essential function in the comanagement of asthma. Barriers to linkages with allergy specialists need to be identified.

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Section: Ar Control Impacts Asthma Controlmentioning

confidence: 99%

Underdiagnosed and Undertreated Allergic Rhinitis in Urban School-Aged Children with Asthma

Esteban

Klein

Kopel

et al. 2014

Pediatric Allergy, Immunology, and Pulmonology

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“…AR impacts asthma morbidity and is associated with poorer asthma control as well as impairment of daily life activity. Thus, treatment of AR may be beneficial in improving asthma control (218,219), which may also support the hypothesis of "one airway, one disease" (220).…”

Section: Ar With Asthmamentioning

confidence: 49%

Chinese Guideline on allergen immunotherapy for allergic rhinitis

et al. 2017

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“…18 Achieving rapid symptom control should improve treatment compliance and improve school performance 24 and asthma control. 25 How MP-AzeFlu should be used in the pediatric AR population is a matter of both physician and patient preference. The choice for first-line use of MP-AzeFlu reflects a "high to low" preference, starting with the pharmacologic treatment option with the best efficacyto-safety ratio and then stepping down if tolerated.…”

Section: Discussionmentioning

confidence: 99%

Safety of a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in children: A randomized clinical trial

Berger

Sher

Gawchik

et al. 2018

allergy asthma proc

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Allergic rhinitis is associated with poor asthma control in children with asthma

Cited by 178 publications

References 35 publications

Underdiagnosed and Undertreated Allergic Rhinitis in Urban School-Aged Children with Asthma

Underdiagnosed and Undertreated Allergic Rhinitis in Urban School-Aged Children with Asthma

Chinese Guideline on allergen immunotherapy for allergic rhinitis

Safety of a novel intranasal formulation of azelastine hydrochloride and fluticasone propionate in children: A randomized clinical trial

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