Allergic Rhinitis

Dunlop, Joan H.; Matsui, Elizabeth C.; Sharma, Hemant

doi:10.1016/j.iac.2015.12.012

Cited by 34 publications

(11 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 21 Outdoor air pollution has been reported to affect the health of patients with allergic diseases, such as asthma, atopic dermatitis (AD), and conjunctivitis. 22 – 25 …”

Section: Discussionmentioning

confidence: 99%

“…In studies on the association between PMs and skin lesion, the mean concentrations of PMs over hours, 27 , 30 , 32 – 34 days, 28 , 35 , 36 and years 31 have been used for analysis. In several studies on the association between air pollution and allergic disease, 22 – 25 the duration of observation is 12 months. Therefore, to calculate the concentration of PMs objectively, we used the daily mean PM concentrations of the previous 12 months for our analysis.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm

Liu¹,

Chan

Hsu

et al. 2017

TCRM

View full text Add to dashboard Cite

Uremic pruritus (UP) is a common and incapacitating symptom in patients undergoing hemodialysis (HD). The pathogenesis of UP is multifactorial and complex. Particulate matter (PM), a major air pollutant, is a mixture of particles with various chemical compositions. PM is associated with several allergic diseases, including dermatitis. To assess the role of PM (PM with a diameter of <10 μm [PM10] and PM with a diameter of <2.5 μm [PM2.5]) and other clinical variables in UP in patients on HD, we recruited 866 patients on maintenance HD (MHD). We analyzed the number of days of mean 24-hour PM10 ≥125 μg/m3/12 months (NDPM10) or the number of days of mean 24-hour PM2.5 ≥35 μg/m3/12 months (NDPM2.5) exceeding the standard level in the past 12 months respectively to determine the association with UP. In a multivariate logistic regression, HD duration, serum ferritin levels, low-density lipoprotein (LDL) levels, and NDPM2.5 ≥116 days/12 months were positively associated with UP. This cross-sectional study showed that the number of days on which the environmental PM2.5 exceeds the standard level might be associated with UP in patients on MHD.

show abstract

“… 21 Outdoor air pollution has been reported to affect the health of patients with allergic diseases, such as asthma, atopic dermatitis (AD), and conjunctivitis. 22 – 25 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm

Liu¹,

Chan

Hsu

et al. 2017

TCRM

View full text Add to dashboard Cite

show abstract

“…Pruritus in MHD patients might occur possibly because skin barrier destruction induces an increase in neuron-specific enolase-immunoreactive nerve fibers in the epidermis 27 . It is well known that outdoor air pollution affects the health of patients with allergic diseases 28 29 30 31 . To our knowledge, this study is the first to show that environmental air pollutants (NO 2 and CO) are positively associated with UP in MHD patients.…”

Section: Discussionmentioning

confidence: 99%

“…Third, air pollution data were collected and calculated from the previous 12 months and 24 months. In several studies on the association between air pollution and allergic disease, the duration of observation is 12-month 28 29 30 31 . In this study, use of previous 24-month air pollutants levels for analysis additionally is consistent with the effects of previous 12-month environmental air pollutants levels.…”

Section: Discussionmentioning

confidence: 99%

Environmental NO2 and CO Exposure: Ignored Factors Associated with Uremic Pruritus in Patients Undergoing Hemodialysis

Huang

Lin

Weng

et al. 2016

Sci Rep

View full text Add to dashboard Cite

Uremic pruritus (UP), also known as chronic kidney disease–associated pruritus, is a common and disabling symptom in patients undergoing maintenance hemodialysis (MHD). The pathogenesis of UP is multifactorial and poorly understood. Outdoor air pollution has well-known effects on the health of patients with allergic diseases through an inflammatory process. Air pollution–induced inflammation could occur in the skin and aggravate skin symptoms such as pruritus or impair epidermal barrier function. To assess the role of air pollutants, and other clinical variables on uremic pruritus (UP) in HD patients, we recruited 866 patients on maintenance HD. We analyzed the following variables for association with UP: average previous 12-month and 24-month background concentrations for nitrogen dioxide (NO2) and carbon monoxide (CO), and suspended particulate matter of <2.5 μm (PM2.5). In a multivariate logistic regression, hemodialysis duration, serum ferritin levels, low-density lipoprotein levels, and environmental NO2/CO levels were positively associated with UP, and serum albumin levels were negatively associated with UP. This cross-sectional study showed that air pollutants such as NO2 and CO might be associated with UP in patients with MHD.

show abstract

“…The perinatal period is a critical time for immune system development and exposure to environmental pollutants during this period can adversely affect immune functions including antibody production and increase the development of allergic phenotypes [57-61]. Dysregulation of immune responses may increase the risk of infectious diseases, hypersensitivity disorders, and even death.…”

Section: The Potential Health Impacts Of Pfcsmentioning

confidence: 99%

Potential health effects of emerging environmental contaminants perfluoroalkyl compounds

Lee

2018

Yeungnam Univ J Med

View full text Add to dashboard Cite

Environmental contaminants are one of the important causal factors for development of various human diseases. In particular, the perinatal period is highly vulnerable to environmental toxicants and resultant dysregulation of fetal development can cause detrimental health outcomes potentially affecting life-long health. Perfluoroalkyl compounds (PFCs), emerging environmental pollutants, are man-made organic molecules, which are widely used in diverse industries and consumer products. PFCs are non-degradable and bioaccumulate in the environment. Importantly, PFCs can be found in cord blood and breast milk as well as in the general population. Due to their physicochemical properties and potential toxicity, many studies have evaluated the health effects of PFCs. This review summarizes the epidemiological and experimental studies addressing the association of PFCs with neurotoxicity and immunotoxicity. While the relationships between PFC levels and changes in neural and immune health are not yet conclusive, accumulative studies provide evidence for positive associations between PFC levels and the incidence of attention deficit hyperactivity disorder and reduced immune response to vaccination both in children and adults. In conclusion, PFCs have the potential to affect human health linked with neurological disorders and immunosuppressive responses. However, our understanding of the molecular mechanism of the effects of PFCs on human health is still in its infancy. Therefore, along with efforts to develop methods to reduce exposure to PFCs, studies on the mode of action of these chemicals are required in the near future.

show abstract

Allergic Rhinitis

Cited by 34 publications

References 47 publications

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm

Environmental NO2 and CO Exposure: Ignored Factors Associated with Uremic Pruritus in Patients Undergoing Hemodialysis

Potential health effects of emerging environmental contaminants perfluoroalkyl compounds

Contact Info

Product

Resources

About

Allergic Rhinitis

Cited by 34 publications

References 47 publications

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of &lt;2.5 &mu;m

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of &lt;2.5 &mu;m

Environmental NO2 and CO Exposure: Ignored Factors Associated with Uremic Pruritus in Patients Undergoing Hemodialysis

Potential health effects of emerging environmental contaminants perfluoroalkyl compounds

Contact Info

Product

Resources

About

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm

Association of uremic pruritus in hemodialysis patients with the number of days of high mean 24-hour particulate matter with a diameter of <2.5 μm