Allergic reactions to henna-based temporary tattoos and their components

Calogiuri, Gianfranco; Foti, Caterina; Bonamonte, Domenico; Nettis, Eustachio; Muratore, L.; Angelini, Gianni

doi:10.3109/08923971003685942

Cited by 17 publications

(20 citation statements)

References 60 publications

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“…For instance, quinone-protein conjugation has been implicated in playing a causative role in the incidence of certain allergic or idiosyncratic drug reactions (Lepoittevin and Benezra 1991;Parrish et al 1997;Petersen 2002). Contact allergic reactions have been linked to 2-hydroxy-2,4-naphthoquinone (henna) (27), a principal ingredient in many types of body dyes (Bolhaar et al 2001;Calogiuri et al 2010). Menadione (21) has been also found to react non-enzymatically with protein thiols that are present in rat plasma and generate ROS that potentiate cellular injury to platelets (Chung et al 1999).…”

Section: Nucleophilic Addition Of Quinonesmentioning

confidence: 98%

The chemical and biological activities of quinones: overview and implications in analytical detection

et al. 2011

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Quinones are a class of natural and synthetic compounds that have several beneficial effects. Quinones are electron carriers playing a role in photosynthesis. As vitamins, they represent a class of molecules preventing and treating several illnesses such as osteoporosis and cardiovascular diseases. Quinones, by their antioxidant activity, improve general health conditions. Many of the drugs clinically approved or still in clinical trials against cancer are quinone related compounds. Quinones have also toxicological effects through their presence as photoproducts from air pollutants. Quinones are fast redox cycling molecules and have the potential to bind to thiol, amine and hydroxyl groups. The aforementioned properties make the analytical detection of quinones problematic. However, recent advances of the available analytical techniques along with the possibility of using labeled compound facilitate their detection hence allowing a better understanding of their action. This review summarizes the current knowledge with respect to the oxido-reductive and electrophilic properties of quinones as well as to the analytical tools used for their analysis. It includes a general introduction about the physiological, and therapeutical functions of quinones. A number of studies are reported to cover the chemical reactivity in an attempt to understand quinones as biologically active compounds. Data ranging from normal analytical methods to study quinones derived from plant or biological matrices to the use of labeled compounds are presented. The examples illustrate how chemical, biological and analytical knowledge can be integrated to have a better understanding of the mode of action of the quinones.

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Section: Nucleophilic Addition Of Quinonesmentioning

confidence: 98%

The chemical and biological activities of quinones: overview and implications in analytical detection

et al. 2011

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“…In fact, an increased number of cases have been reported through temporary henna tattoo application. Therefore, dermatologists, paediatricians and allergists have alerted about the rising frequency of black henna contact allergy [5, 6]. We reviewed the various clinical patterns related to PPD and henna tattoo to investigate the possible link between clinic-morphological pictures and the immunological response to PPD and henna.…”

Section: Discussionmentioning

confidence: 99%

“…The henna is left on the skin to dry for at least 2 h and preferably up to 24 h. The longer henna is put in contact with the skin, the darker the resulting colour will be [3]. As far as allergic reactions are concerned [5, 6], the pure henna is a weak sensitizer and it is poorly responsible for allergic contact dermatitis [7–9], but when para-phenylenediamine (PPD), that is a strong sensitizing agent, is added the frequency of allergic reactions increases. PPD is responsible for professional contact hypersensitivity in photographers, hairdressers and workers manipulating rubber components [10].…”

Section: Introductionmentioning

confidence: 99%

Hypersensitivity reactions due to black henna tattoos and their components: are the clinical pictures related to the immune pathomechanism?

et al. 2017

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Hypersensitivity to para-phenylenediamine (PPD) and related compounds induced by temporary black henna tattoos has become a serious health problem worldwide. Different patterns of sensitization with various clinical aspects are described in literature due to PPD associated to henna tattoo and these manifestations are likely correlated with the immunological and dermatological pathomechanisms involved. Henna is the Persian name of the plant Lawsonia inermis, Fam. Lythraceae. It is a woody shrub that grow in regions of North Africa, South Asia, India and Sri Lanka. Nowadays it is rather frequent to see temporary “tattoos” performed with henna. To make tattoos darker and long-lasting PPD has been associated to henna in tattoo drawings mixtures, so obtaining “black henna”. In these years there has been a rise of contact sensitization to PPD and in medical literature an increased number of cases have been reported on temporary henna tattoo application. Here we review the various clinical patterns related to PPD and henna tattoo, to investigate the possible link between clinic-morphological pictures and the immunological response to PPD and henna. The literature underlines that different clinical manifestations are related to black henna containing PPD, and its derivative products may cause delayed-type as well as immediate-type reactions. Further studies are needed to investigate the relationship between clinical and morphological aspects of PPD contact dermatitis and the T cell subsets predominance.

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“…Den aktive ingrediensen i henna er lawsone (2-hydoksy-1,4-naftokinon). Fargestoffet bindes til hudens keratin, men pigmenteringen forsvinner gradvis når huden fornyes (1,2).…”

Section: Hennaplantenunclassified