Allergic patch test reactions associated with cosmetics: Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004

Warshaw, Erin M.; Buchholz, Heather J.; Belsito, D.; Maibach, Howard I.; Fowler, Joseph F.; Rietschel, Robert L.; Zug, Kathryn A.; Mathias, C. G. Toby; Pratt, Melanie D.; Sasseville, Denis; Storrs, Frances J.; Taylor, James S.; DeLeo, Vincent A.; Marks, James G.

doi:10.1016/j.jaad.2008.07.056

Cited by 94 publications

(74 citation statements)

References 89 publications

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“…An increasing number of studies have linked these health issues to synthetic additives in cosmetics [100][101][102][103][104][105]. The exposure of normal, western skin to twenty-first-century cosmetics, soap, antibiotics, steroids and showering, does appear to have altered the natural microbiota environment of humans, especially in the developed world [14,16].…”

Section: Are Cosmetics a Major Contributor To The Skin Allergy Epidemic?mentioning

confidence: 99%

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

Wallen-Russell

Wallen-Russell²

2017

Cosmetics

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Abstract:There is a skin allergy epidemic in the western world, and the rate of deterioration has increased significantly in the past 5-10 years. It is probable that there are many environmental contributing factors, yet some studies have linked it primarily to the rise in the use of synthetic chemical ingredients in modern cosmetics. Our challenge, therefore, was to find a mechanism to determine the effect these substances have on skin health, and whether they really are a primary cause of long term damage to the skin. The first problem is the lack of any definitive way to measure skin health. Motivated by the overwhelming evidence for a link between deficient gut flora and ill health, we decided to look at whether our skin microbiota could similarly be used as an indicator of skin health. Our research illustrates how microbiota diversity alone can predict whether skin is healthy or not, after we revealed a complete lack of conclusive findings linking the presence or abundance of particular species of microbe to skin problems. This phenomenon is replicated throughout nature, where high biodiversity always leads to healthy ecosystems. 'Caveman' skin, untouched by modern civilisation, was far different to "western" skin and displayed unprecedented levels of bacterial diversity. The less exposed communities were to western practices, the higher the skin diversity, which is clear evidence of an environmental factor in the developed world damaging skin. For the first time we propose benchmark values of diversity against which we can measure skin to determine how healthy it is. This gives us the ability to be able to predict which people are more likely to be prone to skin ailments, and start to test whether cosmetic ingredients and products are a main cause of the skin allergy epidemic.Keywords: biodiversity; skin allergy; benchmark skin health values; effect of synthetic cosmetics on skin; 21st century skin ailments; measure skin health; healthy skin ecosystem; healthy skin bacteria; damaged skin bacteria; perfect skin

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Section: Are Cosmetics a Major Contributor To The Skin Allergy Epidemic?mentioning

confidence: 99%

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

Wallen-Russell

Wallen-Russell²

2017

Cosmetics

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“…Kozmetik ürün alerjileri kadınlarda daha sık görülmektedir. Kozmetiklere karşı mesleksel alerjik reaksiyonlar en sık kuaförlerde görülmekte ve meslekle ilişkili en sık kaynak saç ürünleridir 5 . İki yüz dokuz kuaför üzerinde İtalya'da yapılan bir çalışmada % 43,8'inde saç bakım serilerindeki bir veya daha fazla antijene karşı pozitif yama testi saptanmıştır 6 .…”

Section: Discussionunclassified

“…Kadın ve erkeklerde kozmetiklerle ilişkili en sık 10 allerjen arasında yer almaktadır. Özellikle saç bakım ürünleri ve deri temizleyicileri ile ilgili reaksiyonlarda sık rastlanan bir allerjendir 5 . Kontakt duyarlılık geliştirme sıklığı %3-%7,2 arasında tahmin edilmektedir 2 .…”

Section: Discussionunclassified

Kokamidopropil betain ve kokonat dietanolamide bağlı mesleksel alerjik kontakt dermatit

Doğru¹,

Duman²,

Giniş³

et al. 2013

Turkderm

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Kokamidopropil betain (CAPB) ve kokonat dietanolamid, hindistan cevizi yağından elde edilen, sürfaktan özelliğinde olup şampuan, sıvı sabun ve deri temizleyicilerinde yaygın olarak kullanılan kimyasal maddelerdir. Bu maddelerden özellikle CAPB'e karşı alerjik kontakt dermatit (AKD) gelişebilmektedir. İki maddeye karşı gelişen AKD olgusu literatürde az sayıda bulunmaktadır. Burada ellerde kızarıklık, soyulma, çatlama şikayetleri ile başvuran ve kokamidopropil betain ve kokonat dietanolamid bağlı allerjik kontakt dermatit tanısı konulan olgu sunulmuştur. Sum maryCocamidopropyl betaine (CAPB) and coconut diethanolamide (CDEA), which are manufactured from coconut oil, are widely used as chemical substances with surfactant property in shampoo, liquid soap and skin cleaners. Allergic contact dermatitis (ACD) may occur against these substances, especially cocamidopropyl betaine. ACD developing against these two substances is rarely seen in the literature. Here, we report the case of a patient with ACD caused by CABP and CDEA who presented with complaints of redness, peeling and cracking of the hands. (Turkderm 2013; 47: 180-2)

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“…2) In previous studies, several cosmetic ingredients were reported to have potency to dermal sensitization. [3][4][5][6] A retrospective European survey of allergic contact reaction reports that 165 of 475 patients showed positive reactions to preservatives. 3) In that study, more than half of the cases of positive reaction to preservatives were caused by FA itself or by FA-donor preservatives.…”

Section: Introductionmentioning

confidence: 99%

“…In another report on the patch tests of North American Contact Dermatitis Group, quaternium-15 (QU), an FA-donor preservative, was the most common cosmetic allergen in both males and females. 4) In addition to QU, FA and four more FA-donor preservatives, namely, diazolidinyl urea (DU), dimethyloldimethyl hydantoin (DM), imidazolidinyl urea (IU), and bronopol (BP), were listed as the top 20 allergens with a cosmetic source. It remains controversial whether FA is the major cause of the allergic reaction caused by FA-releasing compounds.…”

Section: Introductionmentioning

confidence: 99%

Survey of Formaldehyde (FA) Concentration in Cosmetics Containing FA-donor Preservatives

Doi

Kajimura

Taguchi

2010

JOURNAL OF HEALTH SCIENCE

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We measured the amount of formaldehyde (FA) in cosmetics containing FA-donor preservatives [imidazolidinyl urea (IU), dimethyloldimethyl hydantoin (DM), diazolidinyl urea (DU), quaternium-15 (QU), and bronopol (BP)] and explored the factors affecting FA release. FA was detected in all the 89 cosmetic products tested. FA concentrations of cosmetics declared to contain DM and DU were significantly higher than those of cosmetics declared to contain IU and BP. Detected FA concentration of samples produced in the U.S.A. was significantly higher than that of samples produced in European countries. A weak proportional relationship was observed between the pH value and the released FA concentration of the cosmetic products containing DM and DU. There were no significant differences in the FA concentrations of various categories of cosmetics (lotion, gel, conditioner, shampoo, body wash, and others). Cosmetics containing a blend of amines, amides, or hydrolyzed proteins together with FA-donor preservatives had a lower FA concentration than the others.

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Allergic patch test reactions associated with cosmetics: Retrospective analysis of cross-sectional data from the North American Contact Dermatitis Group, 2001-2004

Cited by 94 publications

References 89 publications

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

Kokamidopropil betain ve kokonat dietanolamide bağlı mesleksel alerjik kontakt dermatit

Survey of Formaldehyde (FA) Concentration in Cosmetics Containing FA-donor Preservatives

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