Allergic fungal sinusitis in children

Campbell, Jennifer; Graham, Melissa; Gray, Heather C.; Bower, Charles M.; Blaiss, Michael S.; Jones, Stacie M.

doi:10.1016/s1081-1206(10)61237-9

Cited by 57 publications

(45 citation statements)

References 18 publications

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“…A study on 126 patients of ABPA [67] from India does not mention any patient with nasal symptoms, or any attempt to diagnose concomitant AAS. Recently, a study on 20 children with fungal sinusitis [68] identified 11 of them with asthma, but these were not investigated further for the presence of ABPA.…”

Section: Introductionmentioning

confidence: 99%

Allergic Aspergillus sinusitis and its association with allergic bronchopulmonary aspergillosis

Panjabi

Shah

2011

Asia Pacific Allergy

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Allergic Aspergillus sinusitis (AAS) is a three decade old clinicopathologic entity in which mucoid impaction akin to that of allergic bronchopulmonary aspergillosis (ABPA) occurs in the paranasal sinuses. Features such as radiographic evidence of pansinusitis, passage of nasal plugs and recurrent nasal polyposis in patients with an atopic background is suggestive of AAS. Histopathlogic confirmation from the inspissated mucus is a sine qua non for the diagnosis. Heterogeneous densities on computed tomography of the paranasal sinuses are caused by the 'allergic mucin' in the sinuses. Many patients give a history of having undergone multiple surgical procedures for symptomatic relief. The current approach to treatment appears to include an initial surgical debridement followed by postoperative oral corticosteroids for long durations. Although both ABPA and AAS are classified as Aspergillus-related hypersensitivity respiratory disorders, their co-occurrence appears to be an infrequently recognised phenomenon. This could perhaps be attributed to the fact that these two diseases are often treated by two different specialties. A high index of suspicion is required to establish the diagnoses of ABPA and AAS. All patients with asthma and/or rhinosinusitis along with sensitisation to Aspergillus antigens are at an increased risk of developing ABPA and/or AAS. ABPA must be excluded in all patients with AAS and vice versa. Early diagnosis and initiation of appropriate therapy could plausibly alter the course of the disease processes and prevent the possible development of long term sequelae.

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Section: Introductionmentioning

confidence: 99%

Allergic Aspergillus sinusitis and its association with allergic bronchopulmonary aspergillosis

Panjabi

Shah

2011

Asia Pacific Allergy

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“…In an analysis of 155 patients with ABPA from northern India, there was no mention of nasal symptoms [69]. Amongst the paediatric age group, asthma was identified in 20 children with fungal sinusitis but these were not investigated further for the presence of ABPA [207].…”

Section: Allergic Aspergillus Sinusitismentioning

confidence: 99%

Allergic aspergillosis of the respiratory tract

Shah

Panjabi

2014

European Respiratory Review

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“…51 Children with allergic fungal sinusitis may present with proptosis and polyposis. 52 Therapy consists of sinus surgery to remove inflammatory tissue, polyps, and fungus. Immunotherapy, steroids, and topical therapy may provide benefit; however, strong evidence does not exist for these interventions despite their common use to manage these patients.…”

Section: Allergic Fungal Sinusitismentioning

confidence: 99%

Pediatric Rhinosinusitis

Magit¹

2014

Otolaryngologic Clinics of North America

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This review addresses the diagnosis and treatment of acute and chronic rhinosinusitis. Antimicrobial and adjuvant therapies, including topical treatments, are discussed. Surgical intervention is included in the treatment options. Clinical characteristics of rhinosinusitis are presented with an emphasis on history and physical examination. The use of imaging is described with regard to the indications for imaging and selection of imaging modalities. Complications of rhinosinusitis, with management recommendations based on recent data, are described. The evaluation and management of patients with cystic fibrosis and allergic fungal sinusitis is part of the discussion of less common scenarios of patients with sinus disease.

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Allergic fungal sinusitis in children

Cited by 57 publications

References 18 publications

Allergic Aspergillus sinusitis and its association with allergic bronchopulmonary aspergillosis

Allergic Aspergillus sinusitis and its association with allergic bronchopulmonary aspergillosis

Allergic aspergillosis of the respiratory tract

Pediatric Rhinosinusitis

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