Allergic contact stomatitis caused by acrylic monomer in a denture

Koutis, Dennis; Freeman, Susanne

doi:10.1046/j.1440-0960.2001.00517.x

Cited by 67 publications

(47 citation statements)

References 44 publications

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“…These data further support the need for treatment of the acrylic resin, such as polymerization in water or under pressure, [25][26][27] as well as allowing additional polymerization cycles. 5,[25][26][27][28][29] During the preparation of the acrylic appliance, it is also important to keep the right proportion of powder and liquid. 16,25 All these procedures can reduce the frequency of hypersensitivity reactions and help guarantee the patient's well-being.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxicity of Two Autopolymerized Acrylic Resins Used in Orthodontics

Gonçalves

Schmitt

Thomas

et al. 2008

The Angle Orthodontist

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Objective: To test in vitro the null hypothesis that the toxic effect of different acrylic resins used in orthodontics cannot be reduced when a prior elution is performed. Materials and Methods: Three established cell lines were used (HeLa, NIH3T3, and Hep2) and cultured under standard conditions. Resin segments were immersed in a culture medium and left to elute for 24 and 48 hours. Cells were exposed to medium containing eluates for 24 or 48 hours. The 3-(4,5 dimethyl-2-thiazolyl)-2.5-diphenyl-2H-tetrazolium bromide (MTT) assay was used as the cytotoxicity test. Control cells contained standard medium with no eluate. Analysis of variance and Tukey test were used for statistical analysis. Results: Fibroblastic viability was not affected when the elution time was 24 hours, but treatments showed higher cell viability than controls when the elution time was 48 hours. When left to elute for 24 hours, both resins had a cytotoxic effect on epithelial cells, but this effect was not observed when the elution time was 48 hours. Conclusions: The hypothesis was rejected as both tested materials showed lower cytotoxic effect when treated with 48-hour elutes compared with 24-hour elutes, which indicates that a longer elution time reduces resin toxicity.

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Section: Discussionmentioning

confidence: 99%

Cytotoxicity of Two Autopolymerized Acrylic Resins Used in Orthodontics

Gonçalves

Schmitt

Thomas

et al. 2008

The Angle Orthodontist

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“…There are also more obscure exposures unique to the elderly detailed in the literature including benzyl alcohol in hearing aid impression material, [45] acrylic monomer in a denture, [46] coronary stent materials, [47] and implant materials for total knee and total hip arthroplasty. [48,49] Finally, conditions such as urinary fecal incontinence and ostomies following gastrointestinal or urologic procedures disrupt the natural skin barrier, predisposing to both irritant and allergic dermatitides.…”

Section: Medical Co-morbidities In Older Adultsmentioning

confidence: 99%

Contact Dermatitis in Older Adults

Prakash

Davis

2010

American Journal of Clinical Dermatology

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Contact dermatitis is a significant health problem affecting the elderly. Impaired epidermal barrier function and delayed cutaneous recovery after insult enhances susceptibility to both irritants and allergens. Exposure to more numerous potential sensitizers and for greater durations influences the rate of allergic contact dermatitis in this population. Medical co-morbidities, including stasis dermatitis and venous ulcerations, further exacerbate this clinical picture. However, while these factors tend to increase the degree of sensitization in the elderly, waning immunity can actually decrease such a propensity. This interplay of both intrinsic and extrinsic factors makes a generalization on trends for contact dermatitis in older adults challenging. The literature has varying reports on the overall incidence of allergic contact dermatitis with advancing age. Nevertheless, it does clearly show that sensitivity to topical medicaments increases with age. Irritant contact dermatitis studies are more consistent, with less reactivity (to irritants) in older compared with younger skin. Diagnosis of both irritant and allergic contact dermatitis is based on a thorough history, complete skin examination, and comprehensive patch testing. The mainstay of therapy is avoidance of the offending chemical substances and the use of topical along with systemic therapies, depending on the severity of the condition.

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“…However, some authors have reported allergic reactions to an unbound monomer of acrylic materials [22, 29, 30]. …”

Section: Discussionmentioning

confidence: 99%

Determination of Salivary Myeloperoxidase, Immunoglobulin E, and Tumor Necrosis Factor-α after Complete Denture Insertion

et al. 2019

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Objective: To detect activities of salivary myeloperoxidase (MPO) and concentrations of salivary tumor necrosis factor (TNF)-α as indicators of inflammatory reaction and salivary immunoglobulin E as an indicator of allergic reaction after complete insertion of acrylic dentures. Subjects and Methods: Complete dentures were made for a uniform group of elderly patients, and saliva samples were taken immediately before they were given to the patients, as well as 2, 3, 7, and 30 days after insertion of the dentures, with simultaneous monitoring of changes in the oral mucosa. Results: After 7 and 30 days of wearing upper and lower complete dentures, nonsignificant increases in salivary MPO and TNF-α were proven to be indicators of inflammation. No changes were observed in the values of salivary immunoglobulin E during a 30-day observational period, which excluded the appearance of allergic reactions to acrylic materials in the tested group of patients. Conclusion: A nonsignificant increase in the levels of MPO was observed on day 7; it decreased after 30 days. TNF-α also tended to increase in a nonsignificant manner.

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Allergic contact stomatitis caused by acrylic monomer in a denture

Cited by 67 publications

References 44 publications

Cytotoxicity of Two Autopolymerized Acrylic Resins Used in Orthodontics

Cytotoxicity of Two Autopolymerized Acrylic Resins Used in Orthodontics

Contact Dermatitis in Older Adults

Determination of Salivary Myeloperoxidase, Immunoglobulin E, and Tumor Necrosis Factor-α after Complete Denture Insertion

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