Allergic contact sensitivity to quinophthalone

Komamura, Hiromi; Ishii, Masamitsu; Yoshikawa, K.; Iyoda, Masahiko

doi:10.1111/j.1600-0536.1989.tb04653.x

Cited by 7 publications

(3 citation statements)

References 11 publications

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“…One case with body wash specified MI/MCI as the allergen culprit. Thirteen studies with a total of 284 patients identified consumer and medical products, such as hair clips and headband (n = 3), wig adhesive (n = 2), wig (n = 2), continuous positive airway pressure (CPAP) machine strap (n = 2), hair stick (n = 1), spectacle frames (n = 1), aromatherapy (n = 1), leather hat (n = 1), and unspecified (n = 271) as causative scalp allergens 4,6,12,16,91–99 . Common positive patch tests were found for nickel in hair clips and headband, 2-ethylhexyl acrylate and 2-hydroxyethyl methacrylate in wig adhesives, and neoprene/dialkyl thioureas in CPAP straps.…”

Section: Resultsmentioning

confidence: 99%

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

et al. 2022

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Hair products are commonly used to maintain hair health or cosmesis. Products applied to the scalp and hair contain multiple active and inactive ingredients that can potentially cause irritant and/or allergic contact dermatitis. The objectives of this study were to identify and to discuss the most common allergens in scalp and hair applied products causing scalp allergic contact dermatitis (ACD). A PubMed search identified 99 studies, with 3185 patients and 31 categories of scalp products. Hair products reportedly associated with scalp ACD were hair dyes (41%), shampoos (28%), and conditioners (22%). The most commonly reported patch test–positive allergens were p-phenylenediamine (23%), nickel (15%), fragrance mix (13%), balsam of Peru (10%), cocamidopropyl betaine/3-dimethylaminopropylamine (7%), and methylchloroisothiazolinone/methylisothiazolinone (6%). Common symptoms and signs include eczematous lesions, pruritus, and a burning sensation. Medical practitioners should be aware of causative agents to provide appropriate patient education, counseling, and/or treatment.

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Section: Resultsmentioning

confidence: 99%

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

et al. 2022

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“…1 Given the prevalence of documented cases of misdiagnosed or underdiagnosed scalp ACD, it is crucial to accurately differentiate scalp ACD from other conditions. 25,26 Trichoscopy, or dermoscopy of the scalp, is often useful in helping distinguish between inflammatory scalp lesions. Scalp ACD trichoscopy can reveal dotted and comma vessels, simple loops, thin and thick arborizing vessels, white scales, simple red loops, yellow exudate, and generalized erythema.…”

Section: Clinical Presentation and Differential Diagnosismentioning

confidence: 99%

“… 1 Given the prevalence of documented cases of misdiagnosed or underdiagnosed scalp ACD, it is crucial to accurately differentiate scalp ACD from other conditions. 25 , 26 …”

Section: Clinical Presentation and Differential Diagnosismentioning

confidence: 99%

Allergic contact dermatitis of the scalp: a review of an underdiagnosed entity

Hwang,

Beatty,

Khobzei

et al. 2024

International Journal of Women’s Dermatology

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Background: It is hypothesized that scalp allergic contact dermatitis (ACD) in women is commonly mistaken for other disorders due to overlapping symptoms and unique clinical presentations. Objective: This study reviews the potential underdiagnosis and misdiagnosis of scalp ACD and explores ways to improve diagnostic accuracy. Methods: This study conducted an extensive literature review to identify diagnostic challenges, common misdiagnoses, and diagnostic approaches for scalp ACD, focusing on standard versus targeted patch testing techniques. Results: Scalp ACD, often misdiagnosed as seborrheic dermatitis due to similar symptoms, has atypical presentations such as hair thinning, hair loss, and erythematous lesions affecting neighboring regions. Trichoscopy can help distinguish scalp ACD, identifying its patchy distribution of thin white scales, in contrast to the yellow scaling of seborrheic dermatitis. Standardized patch testing further contributes to diagnostic errors, with a study reporting 83% of patients who tested negative with standardized patch tests were positive when using their personal products. Individualized patch testing is more effective in identifying causative allergens and accurately diagnosing scalp ACD. Limitations: It is a retrospective review. Conclusion: Several factors contribute to scalp ACD’s misdiagnosis for conditions such as seborrheic dermatitis. The significant discrepancy in ACD detection rates between personalized and standardized patch tests in women emphasizes the importance of using patient-specific products in diagnostic testing. Incorporating scalp ACD more readily into one’s differential, employing individualized patch testing with trichoscopy, and accounting for neighboring symptomatic areas are all crucial elements in improving diagnostic accuracy for scalp ACD in women.

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Substances that affect the skin: Contact allergy

2016

Meyler's Side Effects of Drugs

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Allergic contact sensitivity to quinophthalone

Cited by 7 publications

References 11 publications

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

Allergic Contact Dermatitis of the Scalp Associated With Scalp Applied Products: A Systematic Review of Topical Allergens

Allergic contact dermatitis of the scalp: a review of an underdiagnosed entity

Substances that affect the skin: Contact allergy

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