Allergic contact dermatitis to methacrylates in ECG electrode dots

Abstract

Acrylates are used widely in acrylic nails, dental restorative materials, paint, varnish, printing ink, adhesives, glue, orthopaedic prostheses, bone cement and diathermy pads. This is the first case of allergic contact dermatitis to methacrylates in electrocardiogram electrode dots reported in the literature.

The role of acrylic acid impurity as a sensitizing component in electrocardiogram electrodes

“…Four cases of ACD induced by disposable electrocardiogram (ECG) electrodes containing acrylates have been reported in the literature . In these reports, the diagnoses were based on positive patch test reactions to the hydrogel part ‘as is’, even if its precise acrylate composition or the relevance of positive patch tests for some (meth)acrylates was not identified.…”

Contact allergy to electrocardiogram electrodes caused by acrylic acid without sensitivity to methacrylates and ethyl cyanoacrylate

“…Since 2001, some cases of allergic contact dermatitis caused by ECG and TENS electrodes have been reported . In these articles, the authors pointed to acrylates as the responsible allergens.…”

“…Contact hypersensitivity to electrocardiogram (ECG) electrodes is rarely reported . It can be caused by the hydrogel part of the electrodes, its adhesive, or its central metal part.…”

“…Figure S3. A representative HPLC chromatogram of sodium acrylate in water (A) and acrylic acid and other impurities upon extraction from the hydrogel in water at 40°C (B).…”

Contact sensitivity to electrocardiogram electrodes due to acrylic acid: A rare cause of medical device allergy

“…Numerous and heterogeneous components of medical devices may cause allergic contact dermatitis (ACD) . Among medical devices used in cardiology, electrocardiogram (ECG) electrodes can cause ACD and many allergens have been reported, for example (meth)acrylates and non‐acrylate components such as propylene glycol, p‐tert ‐butylphenol formaldehyde resin, nickel and rarely hidden allergens (eg, [modified] colophonium or acrylic acid monomers) . In this work, a new case of ACD caused by monomeric acrylic acid (2‐propenoic acid) (CAS no.…”