Allergic contact dermatitis to English ivy (<i>Hedera helix</i>) – a case series

Jones, Joe M.; White, Ian R.; White, J. M. L.; McFadden, John

doi:10.1111/j.1600-0536.2008.01492.x

Cited by 21 publications

(19 citation statements)

References 4 publications

(5 reference statements)

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“…Following a sensitization phase, renewed exposure may then give rise to contact dermatitis. While there have been some case reports relating to ivy allergy, it is thought that the number of cases diagnosed is lower than the actual prevalence, given the lack of standardized diagnostic tests [ 4,5 ] .…”

Section: Discussionmentioning

confidence: 99%

Painful blisters and erosions after gardening

Boehmer¹,

Uretzki²,

Weins³

et al. 2018

J Deutsche Derma Gesell

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Section: Discussionmentioning

confidence: 99%

Painful blisters and erosions after gardening

Boehmer¹,

Uretzki²,

Weins³

et al. 2018

J Deutsche Derma Gesell

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“…Allergic reactions were reported in under 0.5% of cases with no cases of severe anaphylaxis mentioned in any study. This is especially important regarding the fact that hedera helix has been reported to cause allergic contact dermatitis [34, 35] and rarely even occupational asthma in gardeners exposed to the leaves [36]. …”

Section: Discussionmentioning

confidence: 99%

Systematic Review of Clinical Trials Assessing the Effectiveness of Ivy Leaf (Hedera Helix) for Acute Upper Respiratory Tract Infections

Holzinger¹,

Chenot²

2010

Evidence-Based Complementary and Alternative Medicine

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Introduction. Among nonantibiotic cough remedies, herbal preparations containing extracts from leaves of ivy (Hedera helix) enjoy great popularity. Objective. A systematic review to assess the effectiveness and tolerability of ivy for acute upper respiratory tract infections (URTIs). Methods. We searched for randomized controlled trials (RCTs), nonrandomized controlled clinical trials and observational studies evaluating the efficacy of ivy preparations for acute URTIs. Study quality was assessed by the Jadad score or the EPHPP tool. Results. 10 eligible studies were identified reporting on 17463 subjects. Studies were heterogeneous in design and conduct; 2 were RCTs. Three studies evaluated a combination of ivy and thyme, 7 studies investigated monopreparations of ivy. Only one RCT (n = 360) investigating an ivy/thyme combination used a placebo control and showed statistically significant superiority in reducing the frequency and duration of cough. All other studies lack a placebo control and show serious methodological flaws. They all conclude that ivy extracts are effective for reducing symptoms of URTI. Conclusion. Although all studies report that ivy extracts are effective to reduce symptoms of URTI, there is no convincing evidence due to serious methodological flaws and lack of placebo controls. The combination of ivy and thyme might be more effective but needs confirmation.

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“…Again involvement of hands and forearms was most commonly reported, followed closely by involvement of face and neck. However, Jones et al in their case series commented that only 50% of the patients had hands as the primary site of dermatitis (6). Only 2 of the 28 patients were occupationally exposed to common ivy cultivars (16, 17); a third patient was occupationally sensitized to carrot, parsley, and celery with (false) cross‐reactivity to ivy because of the presence of falcarinol in all these species (18).…”

Section: Clinical Featuresmentioning

confidence: 99%

“…In the most recent case series, the authors suggested that allergic contact dermatitis from common ivy may be more common than previously believed, the main reason for this being lack of commercial patch test material (6).…”

mentioning

confidence: 99%

Dermatitis from common ivy (Hedera helix L. subsp. helix) in Europe: past, present, and future

2010

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Common ivy (Hedera helix subsp. helix) is a well-known native and ornamental plant in Europe. Reports on contact dermatitis from ivy have regularly appeared since 1899. Recently, it has been suggested that allergic contact dermatitis from the plant may be under-diagnosed, partly due to lack of commercial patch test allergens. The objective of the article is to present the results of aimed patch testing with the main common ivy allergen, falcarinol, during a 16-year period and review the newer literature. Consecutive patients tested with falcarinol 0.03% petrolatum from May 1993 to May 2009 were included. Cases published since 1987 were retrieved from the PubMed database. One hundred and twenty-seven Danish patients were tested with falcarinol and 10 (7.9%) tested positive. Seven were occupationally sensitized. Between 1994 and 2009, 28 new cases of contact dermatitis from ivy were reported, 2 of which were occupational. Only 11 of the 28 patients were tested with pure allergens. Falcarinol is not only widely distributed in the ivy family, but also in the closely related Apiaceae. Sensitization may occur in childhood or in adults pruning ivy plants or handling them in an occupational setting. In view of the ubiquity of falcarinol-containing plants and the relatively high prevalence of positive reactions in aimed patch testing, falcarinol should be the next plant allergen to be commercially available and included in the plant series worldwide.

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Allergic contact dermatitis to English ivy (Hedera helix) – a case series

Cited by 21 publications

References 4 publications

Painful blisters and erosions after gardening

Painful blisters and erosions after gardening

Systematic Review of Clinical Trials Assessing the Effectiveness of Ivy Leaf (Hedera Helix) for Acute Upper Respiratory Tract Infections

Dermatitis from common ivy (Hedera helix L. subsp. helix) in Europe: past, present, and future

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