“…It is also used in agriculture as a soil fungicide, plant bactericide, and acaricide (Fiege et al, 2000). Studies have shown that some patients tested with a concentration range of 0.3% to 6% transdermal patches (7-147 µM) were allergic to this substance (Schoppelrey et al, 1997). At a high concentration (200 µM), hexachlorophene dramatically increased the IL-1α secretion in the RhE and FTS models ( Figure 4A).…”