Allergic contact dermatitis from <i>Hedera helix</i> L

García, Milagros; Fernández, E.; Navarro, J. A.; Pozo, M. D. Del; Corrés, L. Fernández de

doi:10.1111/j.1600-0536.1995.tb00523.x

Cited by 21 publications

(13 citation statements)

References 4 publications

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“…It contains three powerful irritants and weak sensitizers, namely didehydrofalcarinol and falcarinol (Fig. 31) that have mod- erate sensitizing potentials [310,362,363]. These allergens or related molecules are also present in other members of this family, such as ginseng (Panax ginseng C. Meyer), Schefflera arboricola Hayata [310] or kakuremino (Dendropanax trifidus Makino) [364].…”

Section: Miscellaneous Plantsmentioning

confidence: 97%

Plants and Plant Products

Coz¹,

Ducombs²

2006

Contact Dermatitis

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Section: Miscellaneous Plantsmentioning

confidence: 97%

Plants and Plant Products

Coz¹,

Ducombs²

2006

Contact Dermatitis

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“…However, Jones et al in their case series commented that only 50% of the patients had hands as the primary site of dermatitis (6). Only 2 of the 28 patients were occupationally exposed to common ivy cultivars (16, 17); a third patient was occupationally sensitized to carrot, parsley, and celery with (false) cross‐reactivity to ivy because of the presence of falcarinol in all these species (18). None of the patients were described as atopics, but a 38‐year old man with allergic contact dermatitis from carrot had a 30‐year history of recurrent dermatitis, especially on the hands (19), and a 57‐year old chef had positive radioallergosorbent test results (class II) to carrot and parsley (18).…”

Section: Clinical Featuresmentioning

confidence: 99%

Dermatitis from common ivy (Hedera helix L. subsp. helix) in Europe: past, present, and future

2010

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Common ivy (Hedera helix subsp. helix) is a well-known native and ornamental plant in Europe. Reports on contact dermatitis from ivy have regularly appeared since 1899. Recently, it has been suggested that allergic contact dermatitis from the plant may be under-diagnosed, partly due to lack of commercial patch test allergens. The objective of the article is to present the results of aimed patch testing with the main common ivy allergen, falcarinol, during a 16-year period and review the newer literature. Consecutive patients tested with falcarinol 0.03% petrolatum from May 1993 to May 2009 were included. Cases published since 1987 were retrieved from the PubMed database. One hundred and twenty-seven Danish patients were tested with falcarinol and 10 (7.9%) tested positive. Seven were occupationally sensitized. Between 1994 and 2009, 28 new cases of contact dermatitis from ivy were reported, 2 of which were occupational. Only 11 of the 28 patients were tested with pure allergens. Falcarinol is not only widely distributed in the ivy family, but also in the closely related Apiaceae. Sensitization may occur in childhood or in adults pruning ivy plants or handling them in an occupational setting. In view of the ubiquity of falcarinol-containing plants and the relatively high prevalence of positive reactions in aimed patch testing, falcarinol should be the next plant allergen to be commercially available and included in the plant series worldwide.

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“…Als Alkylanz interagiert es mit Amino-oder Proteingruppen und kann somit eine Wirkung als Hapten haben [7]. Falcarinol kann außer in Efeu auch in Mohrrü-ben und Sellerie vorkommen [5,7] …”

Section: Diskussionunclassified