Allergic contact dermatitis from <i>Dittrichia graveolens</i> (L.) Greuter (stinkwort)

Thong, Haw‐Yueh; Yokota, Miki; Kardassakis, D G; Maibach, Howard I.

doi:10.1111/j.1600-0536.2007.01154.x

Cited by 10 publications

(11 citation statements)

References 15 publications

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“…Molecules from this chemical class are common in many plants belonging to the Compositae family; this can also explain the positive patch test not only for D. graveolens but also for Frullania , Laurus nobillis , and other Compositae. The patient’s skin lesions were treated with clobetasol cream, a class I topical corticoid, and vinyl gloves occlusion at bedtime [ 61 ].…”

Section: Toxicologymentioning

confidence: 99%

Dittrichia graveolens (L.) Greuter, a Rapidly Spreading Invasive Plant: Chemistry and Bioactivity

et al. 2022

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Dittrichia graveolens L. Greuter belonging to the Asteraceae family, is an aromatic herbaceous plant native to the Mediterranean region. This plant species has been extensively studied for its biological activities, including antioxidant, antitumor, antimicrobial, antifungal, anti-inflammatory, anticholinesterase, and antityrosinase, and for its peculiar metabolic profile. In particular, bioactivities are related to terpenes and flavonoids metabolites, such as borneol (40), tomentosin (189), inuviscolide (204). However, D. graveolens is also well known for causing health problems both in animals and humans. Moreover, the species is currently undergoing a dramatic northward expansion of its native range related to climate change, now including North Europe, California, and Australia. This review represents an updated overview of the 52 literature papers published in Scopus and PubMed dealing with expansion, chemistry (262 different compounds), pharmacological effects, and toxicology of D. graveolens up to October 2021. The review is intended to boost further studies to determine the molecular pathways involved in the observed activities, bioavailability, and clinical studies to explore new potential applications.

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Section: Toxicologymentioning

confidence: 99%

Dittrichia graveolens (L.) Greuter, a Rapidly Spreading Invasive Plant: Chemistry and Bioactivity

et al. 2022

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“…The rash healed after application of a topical corticosteroid but, another 2 weeks later red confluent papules appeared, which spread over the anterior trunk (Mateo et al 1995). Reactions can also occur to Dittrichia graveolens (Thong et al 2008). A 32-year-old woman in Italy presented with diffuse dermatitis after use of a massage liniment for 1 month which began to resolve after stopping the product.…”

Section: Allergic Contact Dermatitismentioning

confidence: 99%

Inula helenium, elecampane

Tobyn

2011

Medical Herbs

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“…Although livestock mortality is rare, it appears to be due to enteritis caused by the barbed pappus bristles on the seed, which can puncture the small intestine wall (Philbey and Morton 2000). Stinkwort can also cause contact allergic dermatitis in humans (Thong et al 2008). However, impacts to wildlife, natural ecosystems and working landscapes have not been broadly characterized.…”

Section: Worldwide Invasionmentioning

confidence: 99%