Allergic contact dermatitis due to manganese in an aluminium alloy

Dosil, V. M. Leis; Martínez, R.; Fernández, Rafael Ramos; Ochaíta, Pablo Lázaro

doi:10.1111/j.0105-1873.2006.0729i.x

Cited by 10 publications

(1 citation statement)

References 7 publications

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“…Interestingly, Ni and Mn concentrations above the upper limit in serum were observed in a high proportion of dogs suffering from dermatological disorders. In humans, contact dermatitis associated with Ni is well documented [ 49 , 50 ] and Mn allergic contact dermatitis has also been reported [ 51 , 52 ]. Finally, the Fe concentrations above the normal range in a large proportion of individuals suffering from infection/inflammation and neurological diseases is noteworthy, and the risk to these patients is well documented.…”

Section: Discussionmentioning

confidence: 99%

Serum Concentrations of Essential Trace and Toxic Elements in Healthy and Disease-Affected Dogs

Cedeño

Miranda

Galdo

et al. 2020

Animals

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This study was designed (i) to establish reference ranges for the essential trace element and background levels of toxic element exposure in the healthy/normal dog population, and (ii) to evaluate whether trace element concentrations vary in dogs suffering from different pathologies. Blood serum samples were collected from 187 healthy and diseased dogs at the Veterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Santiago de Compostela (northwest Spain). The samples were acid digested, and the concentrations of trace elements (Co, Cr, Cu, Fe, Mn, Mo, Ni, Se and Zn) and toxic elements (As, Cd, Hg and Pb) were determined by inductively coupled plasma-mass spectrometry (ICP-MS). This enabled us to establish reference ranges for the essential trace elements and the level of toxic element exposure in dogs, and to identify several clinical situations associated with variations in trace elements in serum. Relative to concentrations in healthy control dogs, statistically significant differences were observed in the concentrations of Cu (significantly higher in hepatic, inflammatory/infectious and oncological categories), Mo (significantly higher in renal category), Se (significantly lower in gastrointestinal category) and Zn (significantly lower in gastrointestinal, inflammatory/infectious and renal categories). Trace element concentrations can be a cause or consequence of disease, and the study findings indicate that trace element determination in serum provides useful information on the pathogenesis of certain diseases. Further research on the serum concentrations of trace elements, particularly in relation to other biochemical parameters and diagnostic tools, may provide valuable information for the diagnosis of diseases in dogs and the disease prognosis.

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Section: Discussionmentioning

confidence: 99%

Serum Concentrations of Essential Trace and Toxic Elements in Healthy and Disease-Affected Dogs

Cedeño

Miranda

Galdo

et al. 2020

Animals

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Mangan und seine anorganischen Verbindungen [MAK Value Documentation in German language, 2011]

2012

The MAK‐Collection for Occupational Health and Safety

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Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 50. Lieferung, Ausgabe 2011 Der Artikel enthält folgende Kapitel: Allgemeiner Wirkungscharakter Wirkungsmechanismus Toxikokinetik und Metabolismus Aufnahme, Verteilung, Ausscheidung Metabolismus Erfahrungen beim Menschen Einmalige Exposition Wiederholte Exposition Wirkung auf Haut und Schleimhäute Allergene Wirkung Tierexperlmentelle Befunde und In‐vitro‐Untersuchungen Akute Toxizität Subakute, subchronische und chronische Toxizität Wirkung auf Haut und Schleimhäute Allergene Wirkung Reproduktionstoxizität Genotoxizität Kanzerogenität Bewertung

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Manganese and its inorganic compounds [MAK Value Documentation, 2011]

2015

The MAK‐Collection for Occupational Health and Safety

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The article contains sections titled: Toxic Effects and Mode of Action Mechanism of Action Toxicokinetics and Metabolism Absorption, distribution, elimination Metabolism Effects in Humans Single exposures Repeated exposures Local effects on skin and mucous membranes Allergenic effects Reproductive toxicity Animal Experiments and In vitro Studies Acute toxicity Subacute, subchronic and chronic toxicity Local effects on skin and mucous membranes Allergenic effects Reproductive toxicity Genotoxicity Carcinogenicity Manifesto (MAK value/classification)

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Allergic contact dermatitis due to manganese in an aluminium alloy

Cited by 10 publications

References 7 publications

Serum Concentrations of Essential Trace and Toxic Elements in Healthy and Disease-Affected Dogs

Serum Concentrations of Essential Trace and Toxic Elements in Healthy and Disease-Affected Dogs

Mangan und seine anorganischen Verbindungen [MAK Value Documentation in German language, 2011]

Manganese and its inorganic compounds [MAK Value Documentation, 2011]

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