Allergic Contact Dermatitis, Angioneurotic Edema and Conjunctivitis in a Patient with Autoimmune Thrombocytopenia – A Clinical Case

Abstract

BACKGROUND:Allergic contact dermatitis (ACD) is common in clinical practice, but the aetiology of this disease is quite varied. A leading pathogenetic mechanism is a cell-mediated immunity. The combinations of ACD with other allergic and systemic autoimmune diseases are relatively rare, but these conditions are undoubtedly a professional challenge for practitioners.CASE REPORT:We present a case of ACD combined with other immune-allergic conditions. Aetiology and pathogenesis in these cases are not well understood.CONCLUSION:Based on the data from the general and targeted allergic history, patient’s subjective complaints, clinical picture, allergenic status, paraclinical results, and the presented photo material, the final diagnosis is as follows: Contact allergic dermatitis-acute form.

Contact Dermatitis: Overcoming Challenges of Specific Patients, Deciphering the Results and Reaching a Correct Diagnosis

“…Auto-immune diseases, type I diabetes and contact dermatitis follow a Th1 profile and it is not known if this impacts skin reactivity or disease risk. Patients with autoimmune diseases can develop contact dermatitis (Dermendzhiev et al 2018;Niedziela and Bluvshteyn-Walker 2012;Trindade et al 2004;Kosboth et al 2007).…”