“…135,136 Human uses of propolis are extensive and include cough syrups, lozenges, ointments, vitamins, and cosmetics, such as shampoos, conditioners, lip balms, lotions, and toothpastes. 136 Cases of ACD 137 and ACC 138,139 have been reported in association with propolis, and most cases result from use of propolis-containing products either applied topically (cosmetics) or ingested orally. 135 The main allergen found in propolis is LB-1, which consists of 2 distinct allergens: 3-methyl-2-butenyl caffeate and phenylethyl caffeate.…”