ALLELOCHEMICALS FROM Ageratum conyzoides L. AND Oryza sativa L. AND THEIR EFFECTS ON RELATED PATHOGENS

Kong, Chui‐Hua

doi:10.1007/1-4020-4447-x_11

Cited by 13 publications

(15 citation statements)

References 44 publications

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“…Secondary metabolites are organic compounds that are not directly involved in the normal growth development and reproduction of the plant [1] and through to result from the evolutionary defense put up by plants [2]. Examples include alkaloids, tannins, terpenoids, flavonoids, saponins, phenolics, coumarins, glycosides and steroids.…”

Section: Introductionmentioning

confidence: 99%

GC-MS Analysis of Bioactive Compounds from Whole Plant Chloroform Extract of Ageratum conyzoides

Ahuchaogu¹,

Ogbuehi²,

Obike³

et al. 2018

International Journal of Medicinal Plants and Natural Products

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Section: Introductionmentioning

confidence: 99%

GC-MS Analysis of Bioactive Compounds from Whole Plant Chloroform Extract of Ageratum conyzoides

Ahuchaogu¹,

Ogbuehi²,

Obike³

et al. 2018

International Journal of Medicinal Plants and Natural Products

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“…Ageratum conyzoides is a common annual herbaceous weed belonging to the family Compositae and has a long history of traditional medicinal use [39]. It is a tropical plant commonly found in Central America, the Caribbean, Southeast Asia, South China, India, West Africa, Australia, and South America [40,41]. In many countries, it is utilized in folk medicine, such as that for skin diseases, wound healing, diarrhea, and navel pain in Nigerian children [41][42][43].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Ageratum conyzoides extracts against Giardia duodenalis trophozoites: an experimental study

Pintong

Ruangsittichai

Ampawong

et al. 2020

BMC Complement Med Ther

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Background: Giardia duodenalis causes giardiasis in humans, particularly in developing countries. Despite the availability of treatments, resistance to some of the commercial anti-Giardia drugs has been reported in addition to their harmful side effects. Therefore, novel treatments for giardiasis are required. In this study, we aimed to assess the in vitro activity of crude extracts of Ageratum conyzoides against G. duodenalis trophozoites. Methods: Plants were classified into three groups based on their flower colors: white (W), purple (P), and whitepurple (W-P). Plants were separately cut into leaf (L) and flower (F) parts. Changes in internal organelle morphology of trophozoites following exposure to crude extracts were assessed using transmission electron microscopy (TEM). In subsequent experiments, efficacy of the most active essential oils from crude extracts [half maximal inhibitory concentrations (IC 50) ≤ 100 μg/mL] against G. duodenalis trophozoites was tested. In vitro anti-Giardia assays using essential oils were performed in the same way as those performed using crude extracts. Results: LW-P and FP extracts showed high activity (IC 50 ≤ 100 μg/mL) against G. duodenalis trophozoites, with IC 50 ± SD values of 45.67 ± 0.51 and 96.00 ± 0.46 μg/mL, respectively. In subsequent experiments, IC 50 ± SD values of LW-P and FP essential oils were 35.00 ± 0.50 and 89.33 ± 0.41 μg/mL, respectively. TEM revealed the degeneration of flagella and ventral discs of G. duodenalis trophozoites following exposure to crude extracts. Conclusion: Crude LW-P and FP extracts of A. conyzoides showed the highest activity against G. duodenalis. Exposure to crude extract induced changes in the flagella and ventral discs of G. duodenalis trophozoites, which play important roles in attachment to the surface of mucosal cells. Our results suggest that the tested extracts warrant further research in terms of their efficacy and safety as giardiasis treatment.

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“…It belongs to the family Astreracae, which is an annual herbaceous plant with a long history of traditional use in several countries of the world 2,3 . It is native to Central America, Caribbean, Florida (USA), Southeast Asia, South China, India, Nigeria, Australia, and South America 4,5 . Traditional communities in India, Asia, South America and Africa use this species as an antidysenteric, antilithic 6 , and an antibacterial agents 7,8 .…”

Section: Introductionmentioning

confidence: 99%

“…Traditional communities in India, Asia, South America and Africa use this species as an antidysenteric, antilithic 6 , and an antibacterial agents 7,8 . Ageratum conyzoides has long been known in herbal or folk medicine 7 and its gastroprotective 9 antibacterial 10 antiinflammatory, antianalgesic, antipyretic 5 anticoccidial, 11 and anticonvulsant 12 properties have been reported.…”

Section: Introductionmentioning

confidence: 99%

Studies on the Antimicrobial Activity and Brine Shrimp Toxicity of the Leaves Extract of Ageratum Conyzoides

Daula

Siddiqui

Alam

et al. 2016

Bangla. J. Microbiol.

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The purpose of this study is to evaluate the antimicrobial and cytotoxic properties of the leaves extracts of Ageratum conyzoides L. Ageratum conyzoides has been utilized for the treatment of various ailments. The crude methanolic extract of Ageratum conyzoides, n-hexane, chloroform and ethyl acetate soluble fractions of methanolic extracts were screened for their antimicrobial activity against a number of gram positive and gram negative bacteria by disk diffusion method. The crude extract and n-hexane soluble fraction of crude extract showed significant to moderate antimicrobial activity and chloroform, ethyl acetate soluble fraction of crude extract showed moderate to mild antibacterial activity against gram positive and gram negative bacteria. The zones of inhibition produced by the crude extract (methanolic extract), n-hexane, chloroform and ethyl acetate soluble fractions were found to be 14.89 mm - 19.40 mm, 14 mm - 19.40 mm, 10.66 mm - 13.50 mm and 9.50 mm - 13.26 mm respectively at a concentration of 30 mg/disc. Chloroform, n-hexane and ethyl acetate soluble fractions of methanolic extract of Ageratum conyzoides were screened for antitumor properties using brine shrimp lethality bioassay. A reputed cytotoxic agent vincristine sulphate was used as a positive control. From the results of the brine shrimp lethality bioassay it can be well predicted that nhexane, chloroform and ethyl acetate soluble fractions of methanolic extract of Ageratum conyzoides possess cytotoxic activity on shrimp nauplii. The median lethal concentration (LC50, the concentration at which 50% mortality of brine shrimp nauplii occurred) of n-hexane, chloroform and ethyl acetate were 245.42 mg/ml, 92.61 mg/ml and 6.35 mg/ml, respectively, comparison with positive control vincristine sulphate with 0.839 mg/ml.Bangladesh J Microbiol, Volume 29, Number 2, Dec 2012, pp 98-103

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ALLELOCHEMICALS FROM Ageratum conyzoides L. AND Oryza sativa L. AND THEIR EFFECTS ON RELATED PATHOGENS

Cited by 13 publications

References 44 publications

GC-MS Analysis of Bioactive Compounds from Whole Plant Chloroform Extract of Ageratum conyzoides

GC-MS Analysis of Bioactive Compounds from Whole Plant Chloroform Extract of Ageratum conyzoides

Efficacy of Ageratum conyzoides extracts against Giardia duodenalis trophozoites: an experimental study

Studies on the Antimicrobial Activity and Brine Shrimp Toxicity of the Leaves Extract of Ageratum Conyzoides

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