Alleles at a Mutable Locus Found in Populations of Wild House Mice (
            <i>Mus Musculus</i>
            )

Dunn, L. C.; Morgan, W. C.

doi:10.1073/pnas.39.5.391

Cited by 13 publications

(2 citation statements)

References 3 publications

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“…Two other males produced small numbers of tailless offspring, but also relatively large numbers of Brachys. Since previous 224 G. B. DOOHER, R. J. BERRY, K. ARTZT AJSTD D. BENNETT evidence (Dunn & Morgan, 1953) showed that wild populations frequently possess 'minus modifiers' of the T mutation that lead to phenotypic tailless overlaps of the TI + genotype, and since the high transmission ratio typically associated with wild tf-haplotypes was not evident, we assumed these two males to be wild-type homozygotes. Progeny tests of five of their tailless sons by T/t females resulted in some Brachy (T/ +) offspring, thus confirming that these tailless mice carried a ' + ' allele of T, and therefore were T / + phenotypic overlaps.…”

Section: Histologymentioning

confidence: 99%

A semilethal t-haplotype in the Orkney Islands

et al. 1981

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SUMMARYBreeding tests of wild house mice, trapped from an isolated population from Sanday in the Orkney Islands, have demonstrated the presence of a semilethal t-haplotype designated tw106. Microscopic examination of sperm and testes from a sterile male obtained from this population revealed the histological characteristics typical for homozygotes for semilethal t-haplotypes. This report is the first description of the recovery of a t-haplotype from an island population of wild mice.

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Section: Histologymentioning

confidence: 99%

A semilethal t-haplotype in the Orkney Islands

et al. 1981

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“…Although none of these five males contained lethal talleles, subsequent testing of males wild-trapped from the same source as the Pen F mice revealed one male in a sample of 12 which contained a t-allele. For information on the mode of action of t-alleles seeChesley and Dunn ( 1936), and for their occurrence in wild housemouse populations, Dunn ;mdMorgan (1953).…”

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confidence: 99%

The Population Dynamics of Confined House Mice Supplied with Unlimited Food

Southwick¹

1955

Ecology

113

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The T‐locus – inspiration and distraction?

Erickson

2024

BioEssays

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The T/t locus was a major focus of study by mouse geneticists during the 20th century. In the 70s, as the study of cell surface antigens controlling transplantation antigens was taking off, several laboratories hypothesized that alleles of this locus would control cell surface antigens important for embryonic development. One such antigen, the embryonal carcinoma F9 antigen was said to be an example. Other antigens were described on sperm and embryos that were said to be controlled by alleles at the T/t complex. These findings were later found to be false. The history of the findings and their refutation is described.

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Alleles at a Mutable Locus Found in Populations of Wild House Mice ( Mus Musculus )

Cited by 13 publications

References 3 publications

A semilethal t-haplotype in the Orkney Islands

A semilethal t-haplotype in the Orkney Islands

The Population Dynamics of Confined House Mice Supplied with Unlimited Food

The T‐locus – inspiration and distraction?

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