Allele Frequency Data for Nine STRs Polymorphism in a Gurkha Population of Malaysia

Tuladhar, Bhinu Shova; Haslindawaty, Nur; Nada, B.; Panneerchelvam, Sundararajulu; Nor, Norazmi Mohd

doi:10.1111/j.1556-4029.2006.00247.x

Cited by 2 publications

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References 7 publications

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“…It is well described the importance of knowing the allele distribution of the genetic markers used in forensic laboratories, in the population they will be applied [1] . Diversity of STR loci in some Nepalese population is available in the literature (13,17,20). The present study describes the allele frequencies for 15 short tandem repeat (STR) loci and statistical parameters of forensic interest from a sample of 233 individuals undergoing paternity testing from different regions of Nepal.…”

Section: Introductionmentioning

confidence: 99%

Allele Frequencies of 15 AmpFISTR Identifiler loci in the Nepalese population

Jha¹,

Gonzalez

Rijal³

et al. 2012

Sci World

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Section: Introductionmentioning

confidence: 99%

Allele Frequencies of 15 AmpFISTR Identifiler loci in the Nepalese population

Jha¹,

Gonzalez

Rijal³

et al. 2012

Sci World

Self Cite

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“…The STR population datasets currently available for various population groups in Malaysia are listed in Table 3 . These datasets were mainly produced by researchers from academic institutions [ 8 , 9 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ], and are not part of the RMP database. Mathematical probabilities calculated from these data do indicate that the STR loci tested are reliable for the identification of individuals in criminal cases and for kinship analysis associated with paternity disputes and immigration applications.…”

Section: Dna Population Data For Casework and Paternity Testing Stmentioning

confidence: 99%

Autosomal STR Profiling and Databanking in Malaysia: Current Status and Future Prospects

Hakim

Khan²,

Lalung

et al. 2020

Genes

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Science and technology are extensively used in criminal investigation. From the mid- to late-1980s, one of the scientific discoveries that has had a particularly remarkable impact on this field has been the use of highly variable DNA sequence regions (minisatellites) in the human genome for individual identification. The technique was initially referred to as DNA fingerprinting, but is now more widely referred to as DNA profiling. Since then, many new developments have occurred within this area of science. These include the introduction of new genetic markers (microsatellites also known as short tandem repeats/STRs), the use of the polymerase chain reaction for target amplification, the development of DNA databases (databanking), and the advancement and/or improvement of genotyping protocols and technologies. In 2019, we described the progress of DNA profiling and DNA databanking in Malaysia for the first time. This report included information on DNA analysis regulations and legislation, STR genotyping protocols, database management, and accreditation status. Here, we provide an update on the performance of our DNA databank (numbers of DNA profiles and hits) plus the technical issues associated with correctly assigning the weight of evidence for DNA profiles in an ethnically diverse population, and the potential application of rapid DNA testing in the country. A total of 116,534 DNA profiles were obtained and stored in the Forensic DNA Databank of Malaysia (FDDM) by 2019, having increased from 70,570 in 2017. The number of hits increased by more than three-fold in just two years, where 17 and 69 hits between the DNA profiles stored in the FDDM and those from crime scenes, suspects, detainees, drug users, convicts, missing persons, or volunteers were recorded in 2017 and 2019, respectively. Forensic DNA analysis and databanking are thus progressing well in Malaysia and have already contributed to many criminal investigations. However, several other issues are discussed here, including the need for STR population data for uncharacterized population groups, and pilot trials for adopting rapid DNA profiling technology. These aspects should be considered by policy makers and law enforcement agencies in order to increase the reliability and efficiency of DNA profiling in criminal cases and in kinship analysis in Malaysia.

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Allele Frequency Data for Nine STRs Polymorphism in a Gurkha Population of Malaysia

Abstract: POPULATION: Random Gurkha Population, Rawang, Malaysia.

Cited by 2 publications

References 7 publications

Allele Frequencies of 15 AmpFISTR Identifiler loci in the Nepalese population

Allele Frequencies of 15 AmpFISTR Identifiler loci in the Nepalese population

Autosomal STR Profiling and Databanking in Malaysia: Current Status and Future Prospects

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