All roads bring to Rome: a different way for predicting success in the therapy of obesity through psychological features

Rotella, Francesco; Lazzeretti, Lisa; Barbaro, Valeria; Castellini, Giovanni; Bigiarini, Michela; Cresci, Barbara; Ricca, Valdo; Rotella, Carlo Maria; Mannucci, Edoardo

doi:10.1007/s40618-014-0130-5

Cited by 6 publications

(13 citation statements)

References 38 publications

(51 reference statements)

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“…T4 was also characterized by the highest levels in novelty seeking and the lowest levels in persistence. This result is coherent with the evidence reported in the scientific literature suggesting that the worse pre‐surgery psychological clinical state is predictive of poorer post‐surgery outcomes (Agüera et al, ; Gade, Rosenvinge, Hjelmesæth, & Friborg, ; Rotella et al, ).…”

Section: Discussioncontrasting

confidence: 99%

Weight Loss Trajectories in Bariatric Surgery Patients and Psychopathological Correlates

García-Ruiz-de-Gordejuela

Agüera

Granero

et al. 2017

Euro Eating Disorders Rev

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This study aimed to explore the empirical trajectories of body mass index (BMI) 1 year following bariatric surgery (BS) and to identify the risk factors for each trajectory. The study included 115 patients with severe obesity who underwent BS. Assessment included metabolic variables, psychopathological and personality measures. Growth mixture modelling identified four separated trajectories for the percentage of total weight loss course shape (namely, T1 'good-fast', T2 'good', T3 'low' and T4 'low-slow'). After adjusting for BS subtype and metabolic baseline state, T1 and T2 registered less eating and general psychopathology. T1 was characterized by the lowest scores in novelty seeking and self-transcendence, whereas T4 was defined by the highest scores in novelty seeking and the lowest scores in persistence. Our findings suggest that psychological state prior to BS is predictive of BMI trajectories during the 12 months following BS. These results could be useful in developing more efficient interventions for these patients. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.

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Section: Discussioncontrasting

confidence: 99%

Weight Loss Trajectories in Bariatric Surgery Patients and Psychopathological Correlates

García-Ruiz-de-Gordejuela

Agüera

Granero

et al. 2017

Euro Eating Disorders Rev

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“…Not surprisingly, a higher degree of adherence to various components of LMT and early weight loss have both been associated with better long-term outcomes. 40–44 Psychosocial factors associated with improved weight loss response in adults include greater social support; 45 higher baseline exercise self-efficacy, 46 dietary restraint, 47 flexible cognitive restraint, 48 and motivation (in men); 48 lower levels of psychopathology (in women), 49 emotional eating, 48 and disinhibition; 47 and fewer exercise barriers 48 and previous dieting attempts. 46 In children, higher levels of global self-worth have positively predicted weight loss response, 50 while higher levels of disordered eating in the child and the presence of psychopathology in the mother have been identified as negative predictors.…”

Section: Heterogeneity In the Effectiveness Of Interventions For The mentioning

confidence: 99%

“…Increased baseline appetite and decreased satiety predict better response, while the presence of disordered eating and psychopathology predict worse response to several interventions. 47–49,51,85,95,105,123 While these identified ‘primordial’ predictors represent the beginning of our understanding into person-specific characteristics predictive of weight loss response, many are not specific enough to help us tailor therapy. For example, given that increased hunger predicts greater weight loss response to exenatide, 85 topiramate, 89 and phentermine, 94 adding this variable to a pharmacotherapy selection algorithm may not help in the decision-making between these three options.…”

Section: Gaps and Opportunities For Future Research In The Developmenmentioning

confidence: 99%

Precision medicine in adult and pediatric obesity: a clinical perspective

Bomberg

Ryder

Brundage

et al. 2019

Therapeutic Advances in Endocrinology

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It remains largely unknown as to why some individuals experience substantial weight loss with obesity interventions, while others receiving these same interventions do not. Person-specific characteristics likely play a significant role in this heterogeneity in treatment response. The practice of precision medicine accounts for an individual’s genes, environment, and lifestyle when deciding upon treatment type and intensity in order to optimize benefit and minimize risk. In this review, we first discuss biopsychosocial determinants of obesity, as understanding the complexity of this disease is necessary for appreciating how difficult it is to develop individualized treatment plans. Next, we present literature on person-specific characteristics associated with, and predictive of, weight loss response to various obesity treatments including lifestyle modification, pharmacotherapy, metabolic and bariatric surgery, and medical devices. Finally, we discuss important gaps in our understanding of the causes of obesity in relation to the suboptimal treatment outcomes in certain patients, and offer solutions that may lead to the development of more effective and targeted obesity therapies.

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“…Under these conditions, obese patients reach the goal of loosing weight more frequently than obese subjects who did no display these traits. However, in a more recent study, the same authors found that the test seems to be capable to predict weight loss only in men, suggesting that in women, other psychiatric or psychological factors may play a greater role [31] . Since the questionnaire has been published in the last few years, it has not been widely used or tested in populations different from those used for its validation.…”

Section: Self-motivationmentioning

confidence: 95%

“…On the other hand, there is poor evidence for QoL as treatment predictor. Only few studies explored QoL as a predictor of success in obesity treatment and Teixeira et al [63] found an association between pretreatment quality of life measures and long-term outcomes of a lifestyle weight loss programs; whereas Rotella et al [31] did not confirm this result.…”

Section: Quality Of Lifementioning

confidence: 98%

Assessment of psychological predictors of weight loss: How and what for?

Lazzeretti¹,

Rotella²,

Pala³

et al. 2015

WJP

Self Cite

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Obesity is a multifactorial disease and the prominent factors playing a role in its pathogenesis are biological, environmental and psychological. There is a growing interest in understanding psychological functioning of obese subjects and the influence of psychological factors on treatment outcome. The aim of the present narrative review is to critically analyze the current literature, in order to point out the most common psychological constructs studied in obesity and to give an overview of the main existing tools investigating psychological features which have been considered significant for the prediction of success in weight loss and maintenance programs in obese patients. In this framework, the most common psychological constructs studied are: self-motivation, self-efficacy, locus of control, health related quality of life, self-esteem, self-control, concerns about body image, outcome expectations, and personality traits. These features have been explored through a wide variety of psychometric instruments. However, as an overall, studies evaluating the association between psychological features and treatment outcome failed to give consistent results. A possible explanation may consist on the fact that many tools widely used to explore psychological features were not specifically designed for obese patients and none of them was comprehensive of all possible psychological features involved. The identification of well-defined subgroups of patients and the validation of more reliable and comprehensive tools, specifically designed for obese subjects, should be forecasted in order to reach a better knowledge of psychological functioning of obese individuals and to improve the outcome of weight loss programs.

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All roads bring to Rome: a different way for predicting success in the therapy of obesity through psychological features

Cited by 6 publications

References 38 publications

Weight Loss Trajectories in Bariatric Surgery Patients and Psychopathological Correlates

Weight Loss Trajectories in Bariatric Surgery Patients and Psychopathological Correlates

Precision medicine in adult and pediatric obesity: a clinical perspective

Assessment of psychological predictors of weight loss: How and what for?

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