In
spite of recent advancements in artificial neural
networks (ANNs),
the energy efficiency, multifunctionality, adaptability, and integrated
nature of biological neural networks remain largely unimitated by
hardware neuromorphic computing systems. Here, we exploit optoelectronic,
computing, and programmable memory devices based on emerging two-dimensional
(2D) layered materials such as MoS2 to demonstrate a monolithically
integrated, multipixel, and “all-in-one” bioinspired
neural network (BNN) capable of sensing, encoding, learning, forgetting,
and inferring at minuscule energy expenditure. We also demonstrate
learning adaptability and simulate learning challenges under specific
synaptic conditions to mimic biological learning. Our findings highlight
the potential of in-memory computing and sensing based on emerging
2D materials, devices, and integrated circuits to not only overcome
the bottleneck of von Neumann computing in conventional CMOS designs
but also to aid in eliminating the peripheral components necessary
for competing technologies such as memristors.