“…Alkyl (poly)glycosides (APGs) are a type of environmentally friendly non-ionic surfactant, which contain a hydrophilic glycosyl head and a hydrophobic alkyl tail. − As a new type of green non-ionic surfactant, APGs and the related anomerically pure 1,2- cis or 1,2- trans alkyl glycosides (AGs) have the following features: low surface activity, good foamability, good thickening effect, low/no toxicity, low/no irritation, complete biodegradation, good compatibility with skin, mildness in the formulation, strong alkaline resistance, and excellent caustic stability. − They are widely used in daily cosmetics, the food processing industry, pharmaceuticals, etc. − However, APGs are easy to crystallize and precipitate under low temperatures. Also, their water solubility decreases with increasing the alkyl chain length, and they even have not water solubility with a longer alkyl chain. , At the same time, their structure–property−performance relationship is rather ambiguous and uncertain as a result of their mixtures of homologues, anomers, and isomers.…”