Alkoxycarbonylation-triggered nitrile insertion/remote C(sp²)–H and C(sp³)–H functionalization to access esterified quinazolinones and amidines

Abstract

A new alkoxycarbonyl radical triggered nitrile insertion/remote C(sp2)-H and C(sp3)-H functionalization reaction is developed. With this method, a broad range of ester-containing fused quinazolinones and bicyclic amidines are prepared through...