Alkaloids of Desmodium triflorum

Ghosal, Shibnath; Srivastava, R. S.; Banerjee, Putul; Dutta, Sunil

doi:10.1016/s0031-9422(00)97411-9

Cited by 20 publications

(10 citation statements)

References 4 publications

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“…Previous phytochemical investigations on D. triflorum have been able to isolate astragalin, cosmossiin, tectorigenin (Ogbeide and Parvez, 1992), 2 -O-glucosylvitexin (Adinarayana and Syamasundar, 1982), 2-O-β-xylosylvitexin (Sreenivasan and Sankarasubramanian, 1984), vitexin, genistin, aliphatic alcohols, aliphatic acids, ursolic acid, oleanolic acid, campesterol, stigmasterol, β-sitosterol, campesterol-3-O-β-D-glucose, stigmasterol-3-O-β-D-glucose, sitosterol-3-O-β-D-glucose and (+)-pinitol (Chio and Huang, 1995). Alkaloids such as hypaphorine, N,N-dimethyltryptophan, betaine, choline, β-phenethylamine, and N,N-dimethyltryptamine oxide have also been isolated from D. trflorum (Ghosal et al, 1971). In mainland China, three plants in the Desmodium genus (D. styracifolium, D. trifolium, D. gangeticum) were studied for their affects on cigarette smoke, free radicals and their inhibitory rates on lipid peroxidation (Mao et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Antiproliferative Activities of Desmodium triflorum (L.) DC

Lai

Huang

et al. 2010

Am. J. Chin. Med.

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This study evaluated the antioxidant and antiproliferative activities of the crude extract and fractions of Desmodium triflorum (L.) DC. The total phenolic content, 1,1-diphenyl-2- picrylhydrazyl hydrate (DPPH) free radical scavenging activity, trolox equivalent antioxidant capacity (TEAC), reducing power, total flavonoid content of D. triflorum were evaluated for the exploration of its antioxidant activities. Furthermore, its antiproliferative activities were investigated through the MTT method. It was compared with the antioxidant capacities of known antioxidants, including catechin, alpha-tocopherol, trolox and ascorbic acid. Among all fractions, ethyl acetate fraction was the most active in scavenging DPPH and TEAC radicals, of which 0.4 mg was equivalent to 186.6 +/- 2.5 microg and 82.5 +/- 2.1 microg of alpha-tocopherol and trolox respectively. The total phenolic and flavonoid contents of the crude extract were equivalent to 36.60 +/- 0.1 mg catechin and 45.6 +/- 0.6 mg rutin per gram respectively. In the reducing power assay, 1.25 mg of crude extract was similar to 61.2 +/- 0.3 microg of ascorbic acid. For the assessment of the safety and toxicity of D. triflorum, LD(50) of the crude extract was greater than 10 g/kg when administered to mice through gastric intubation. The above experimental data indicated that D. triflorum was a potent antioxidant medicinal plant, and such efficacy may be mainly attributed to its polyphenolic compounds.

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Section: Introductionmentioning

confidence: 99%

Antioxidant and Antiproliferative Activities of Desmodium triflorum (L.) DC

Lai

Huang

et al. 2010

Am. J. Chin. Med.

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“…From the leaves, catechin 3'-O-gallate (60), catechin 4'-O-gallate (61), catechin (62), gallocatechin 3'-O-gallate (63), gallocatechin 4'-O-gallate (64), gallocatechin 7,3'-O-gallate (65), gallocatechin 7,4'-O-gallate (66), and epigallocatechin 3-O-gallate (68) were isolated. Gallocatechin (67), epicatechin 3-O-gallate (69), procyanidin B1 (70), procyanidin B3 (71) and procyanidin B4 (72), together with the previously reported catechin (62), gallocatechin 4'-O-gallate (64), and gallocatechin 7,4'-O-gallate (66), were also isolated from the pods [22]. Due to the high content of anti-oxidant flavonoids in the leaves and pods, application of A. jiringa as a functional food appears promising.…”

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confidence: 53%

“…The plant contains alkaloid, flavonoids, saponin, and tannins [63]. β-Phenethylamine, hypaphorine methyl ester (43), hypaphorine (45), trigonelline (46), betaine and choline were found to be the major alkaloids in the leaves and roots of D. triflorum [64]. Compounds 43 -45 were also isolated from the seeds of A. precatorius [11][12][13].…”

Section: Desmodium Triflorummentioning

confidence: 99%

Leguminous Plants in the Indonesian Archipelago: Traditional Uses and Secondary Metabolites

Bahtiar

Vichitphan

Han

2017

Natural Product Communications

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Indonesia is one of the richest countries with respect to plants resources. People from various ethnic, language, and religious groups have used the plants as alternative medicines, health foods and beverages for hundreds of years. To establish modern application for these understudied plant resources, ethnopharmacological data from more than 40 leguminous plants in Indonesia, spanning the western to the eastern parts of the Indonesian archipelago, were reviewed. In particular, bioactive secondary metabolites, including flavonoids, were described in detail to promote research into these plants as functional foods, nutraceuticals, and medicines.

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“…The important constituents of the PC extract are the metabolites alpha-1-barrigenol, camelliagenin A, stigmasterol [21], flavonoids, steroids, terpenoids and cardiac glycosides which have been isolated from this plant [22][23][24] and used in the treatment for strangury, urinary calculi and ulcers. The important constituents of the DT extract are alkaloids and flavonoids compounds [25,26] which are known to have many medicinal properties and are used for the treatment of muscle spasms, diarrhea, dysentery, wounds, and abscesses [27,28], and as an analgesic and anti-inflammatory [29,30].…”

Section: Introductionmentioning

confidence: 99%

Spectroscopic Investigations of Physicochemical Interactions on Mild Steel in an Acidic Medium by Environmentally Friendly Green Inhibitors

Pitchai¹,

Vivekananthan

Gopiraman

et al. 2012

J Surfact & Detergents

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The influences of Polycarpaea corymbosa (PC) and Desmodium triflorum (DT) leaf extracts on the corrosion behavior of mild steel (MS) in 1.0 M HCl was investigated by weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) measurements. The effect of temperature on the corrosion behavior of MS in 1.0 M HCl with the addition of plant extracts was studied in the temperature range of 300 K-320 ± 1 K. The results revealed that PC and DT were excellent green inhibitors and the inhibition efficiencies obtained from weight loss and electrochemical experiments were in good agreement. Inhibition efficiencies up to 91.78 % for PC and 92.99 % for DT were obtained. Potentiodynamic polarization studies revealed that both the inhibitors behaved as mixed-type inhibitors. Adsorption behavior of these green inhibitors on the MS surface was found to obey the Langmuir adsorption isotherm. The thermodynamic parameter values of free energy of adsorption (DG ads ) and enthalpy of adsorption (DH ads ) revealed that each inhibitor was adsorbed on the MS surface via both chemisorption and physisorption mechanisms. The adsorption mechanism of inhibition was supported by FT-IR, UV-Visible, WAXD and SEM-EDS.

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Alkaloids of Desmodium triflorum

Cited by 20 publications

References 4 publications

Antioxidant and Antiproliferative Activities of Desmodium triflorum (L.) DC

Antioxidant and Antiproliferative Activities of Desmodium triflorum (L.) DC

Leguminous Plants in the Indonesian Archipelago: Traditional Uses and Secondary Metabolites

Spectroscopic Investigations of Physicochemical Interactions on Mild Steel in an Acidic Medium by Environmentally Friendly Green Inhibitors

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