Alkaloids of Delphinium corumbosum

Uraline, a New Norditerpenoid Alkaloid from Aerial Parts of Delphinium uralense Nevski

“…The treatment of the evaporated mother liquor (8.43 g) with 10% HClO 4 solution in ethanol (70 ml) yielded methyllycaconitine perchlorate (3.85 g, 24% of SA calculated for methyllycaconitine). All the physicochemical characteristics of the isolated delcorine and methyllycaconitine ( 1 H and 13 C NMR, IR, and mass spectra) were identical to those reported in [2,3]. The alkaloids from mother liquor were converted into free bases; dissolved in 5% H 2 SO 4 (100 ml); and fractionally neutralized with a Na 2 CO 3 solution to pH 6, 7 and 9 with subsequent extraction with benzene and methyl-tert-butyl ether and with 10% NaOH to pH 12 with subsequent extraction with dichloroethane to give fractions A: pH 6, 4.02 g (benzene) and 0.12 g (methyl-tert-butyl ether); pH 7, 0.17 g (benzene) and 0.03 g (methyl-tert-butyl ether); pH 9, 0.03 g (benzene); and pH 12, 0.08 g (dichloroethane).…”

“…section) complex [1]. 2 We have studied the aerial parts of the herb gathered at the beginning of flower-bud formation in the territory of Southern Urals (the Zilair plateau). The literature available for us contain no information on alkaloids from this herb.…”

Three New C19-Diterpenoid Alkaloids from Delphinium Bonvalotii

“…In earlier phytochemical studies [2,3], nine diterpenoid alkaloids, namely, bonvalotine (4), bonvalol, bonvalone, delbotine, delboxine, delbonine, delbine, deltamine, and deltaline were characterized. Further investigation has now led to the isolation of three new C 19 -diterpenoid alkaloids, bonvalotidine A (1), bonvalotidine B (2), and bonvalotidine C (3), together with sixteen additional known alkaloids [4][5][6][7][8][9][10][11][12][13][14][15], delpheline (5), delsoline (6), deltatsine (7), delphatine (8), lycoctonine (9), browniine (10), anthranoyllycotonine (11), methyllycaconitine (12), delsemine A (13), delsemine B (14), tuguaconitine (15), pacinine (16), 6-acetyldelcorine (17), 6-acetyldelpheline (18), 6-deoxydelpheline (19), and 6-dehydrodeltamine (20) (Figure 1). The isolation and structure determination of bonvalotidines A-C is reported herein.…”