Alkaloids of Aconitum laeve and their anti-inflammatory, antioxidant and tyrosinase inhibition activities

Anti-Inflammatory and Antioxidant Activities of Methanol Extracts and Alkaloid Fractions of four Mexican Medicinal Plants of Solanaceae

“…Although antioxidant activity of alkaloids is also documented (Shaheen et al, 2005;Oloyede et al, 2010;Maiza-Benabdesselam et al, 2007), these compounds did not have a reputation as good antioxidant agents; even those of pyridine type, like nicotine, are rather credited with pro-oxidant activity (Sudheer et al, 2005). This is in accordance with the results obtained in the present study.…”

“…Antioxidants are known to suppress inflammation in a rat arthritis model and in a mouse model of contact hypersensitivity (Yoshino et al, 2006). Other studies indicate that alkaloids and especially phenolics contained in medicinal plants have antioxidant and/or anti-inflammatory activity (Kao et Shaheen et al, 2005). Relationship between these two biological activities has also been established (Scalbert et al, 2005;Jensen et al, 2008).…”

Essential oil compositions and antioxidant properties of the roots of twelve AnatolianPaeoniataxa with special reference to chromosome counts

“…Computer matching against commercial (Wiley GC/MS Library; Adams Library; MassFinder 3 Library) (Jennings & Shibamoto, 1980;Adams, 2001;König et al, 2004) and in-house Başer Library of Essential Oil Constituents built up by genuine compounds and components of the known oils, as well as MS literature data (Joulain & König, 1988;McLafferty & Stauffer, 1989;ESO, 2000;Shaheen et al, 2005) were employed in identification of essential oil composition.…”

Preliminary evaluation of the antispasmodic and lipoxygenase inhibitory effects of some selected medicinal plants

“…Inhibition increased linearly with increasing concentration of the extract to a maximum effect of 95% inhibition of contractions at 0.25 mg/mL final bath concentration (Table 1). Alkaloids have been reported to be the principal class of constituents from A. laeve (Ulubelen et al, 2002;Shaheen et al, 2005). Indeed, phytochemical studies of this extract have led us to the isolation of several alkaloids; the exact structures of which are currently under investigation.…”