Alkaline areas in gastric mucosa after gastric surgery

Capper, W. M.; Bütler, Thomas; Buckler, K. G.

doi:10.1136/gut.7.3.220

Cited by 25 publications

(6 citation statements)

References 2 publications

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“…Gallereflux und Alkalisierung des sauren Milieus werden urs/ichlich ffir die Schleimhautalteration und die Entstehung eines Ulcus ventriculi angesehen [2,16,3,14]. Ein erh6hter Gallereflux bei Ulcus ventriculi-Patienten ist mehrfach beschrieben worden [16,24].…”

Section: Diskussionunclassified

Lebercirrhose und duodenogastrischer Reflux ?Zum Problem des hepatogenen Ulcus

Kliems

Feld

Bergmann

1983

Langenbecks Arch Chiv

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Patients suffering from liver cirrhosis and patients showing no signs of liver or stomach disease (control group) were quantitatively examined for duodenogastric reflux. The duodenogastric reflux was measured by means of bile tracers. The bile tracer used in this study was the tricarbocyanin dye indocyningreen (ICG). The intra-gastric concentration of ICG was photometrically measured after gastric acid was suctioned through a stomach tube. The duodenogastric reflux was calculated in percent in terms of the infused and the biliary secreted ICG amount respectively. Bromthalein was used as an additional tracer in order to control the efficiency of peptic acid removal. A total of 15 patients suffering from liver cirrhosis and 6 patients who showed no signs of stomach or liver disease (control group) were examined. The patients with liver disease showed a reflux of 2.85% +/- 0.76%, the control group (n = 6) showed a reflux of 0.45% +/- 0.39%. The difference is statistically significant (P less than 0.05). Bromthalein aspiration by all patients with liver cirrhosis was 87.95 +/- 2.78% of the amount infused.

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Section: Diskussionunclassified

Lebercirrhose und duodenogastrischer Reflux ?Zum Problem des hepatogenen Ulcus

Kliems

Feld

Bergmann

1983

Langenbecks Arch Chiv

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“…Bei einem geringen Anteil der Patienten mit Ulcus duodeni, vor allem aber in der Mehrzahl beim Ulcus ventriculi wurde ein duodenogastrischer Reflux gefunden [4,19]. Auch nach verschiedenen chirurgischen Eingriften am Magen, die zu geeigneten funktionellen und anatomischen Ver~inderungen fiihren, wurde ein Reflux von alkalischem Sekret beobachtet [3,7,12,21]. Die zerst6rende Wirkung der Galle auf die Magenschleimhaut wiesen schon Smith [20] und Grant u. Mitarb.…”

Section: Diskussionunclassified

“…Auch nach operativen Eingriffen wurden durch Gallereflux indu-zierte ,,alkalische Zonen" [3] nachgewiesen. Nach Magenresektion nach Billroth II mit hinterer Gastroenteroanastomose ohne gaUeableitende Braunsche Anastomose, nach einfacher Gastroenteroanastomose, besonders jedoch nach der Resectio Billroth I, ist das klinische Krankheitsbild der alkalischen Refluxgastritis bekannt [7,21].…”

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Duodenogastrischer Reflux nach Vagotomie und Pyloroplastik

Rothmund

Deisler

Kaufmann

et al. 1976

Langenbecks Arch Chiv

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In 27 patients after selective or truncal vagotomy and pyloroplasty the occurrence of duodenogastric reflux was checked by two methods, by the measurement of Bromsulphalein (BSP)-concentration in the gastric aspirate after BSP was given intravenously and by instillation of a barium meal in the second part of the duodenum followed by upper GI-series. In 20 of 23 patients reflux was recorded radiologically, in 18 of 27 patients reflux was shown by the BSP-Method. Proven bile reflux was associated with major postoperative discomfort, such as epigastric fullness, nausea and epigastric pain, it was also associated with gastritis as shown by microscopic examination of biopsies taken from the antrum. It is recommended to consider duodenogastric reflux as a possible reason for patients complaints after vagotomy and pyloroplasty. To avoid those complaints the preference of proximal gastric vagotomy without pyloroplasty is supported, if preoperative gastric emptying is not impaired.

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“…We were able to show that a similar sequence occurred when gastroenterostomy (Billroth I) or Polya operations were done in man. Later a patient on whom a Roux-en-Y had been done had to have a vagotomy; she had no alkaline area in her stomach at all (Capper et al 1966).…”

mentioning

confidence: 99%

Significance of the Pyloric Valve in Gastro-Oesophageal Pathology

1969

Proceedings of the Royal Society of Medicine

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Alkaline areas in gastric mucosa after gastric surgery

Cited by 25 publications

References 2 publications

Lebercirrhose und duodenogastrischer Reflux ?Zum Problem des hepatogenen Ulcus

Lebercirrhose und duodenogastrischer Reflux ?Zum Problem des hepatogenen Ulcus

Duodenogastrischer Reflux nach Vagotomie und Pyloroplastik

Significance of the Pyloric Valve in Gastro-Oesophageal Pathology

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