We investigate a class of new ((⋅, ⋅), (⋅, ⋅))-mixed cocoercive operators in Hilbert spaces. We extend the concept of resolvent operators associated with (⋅, ⋅)-cocoercive operators to the ((⋅, ⋅), (⋅, ⋅))-mixed cocoercive operators and prove that the resolvent operator of ((⋅, ⋅), (⋅, ⋅))-mixed cocoercive operator is single valued and Lipschitz continuous. Some examples are given to justify the definition of ((⋅, ⋅), (⋅, ⋅))-mixed cocoercive operators. Further, by using resolvent operator technique, we discuss the approximate solution and suggest an iterative algorithm for the generalized mixed variational inclusions involving ((⋅, ⋅), (⋅, ⋅))mixed cocoercive operators in Hilbert spaces. We also discuss the convergence criteria for the iterative algorithm under some suitable conditions. Our results can be viewed as a generalization of some known results in the literature.