Alginate hydrogel incorporating cellulose nanofiber from solid waste agar industry for hydrophobic antibiotic delivery: Synthesis and characterization

Putra, Budiono Ujaya; Hardiningtyas, Safrina Dyah; Hastuti, Novitri; Ramadhan, Wahyu; Uju,; Razi, Muhamad Alif; Agustini, Luciasih

doi:10.1016/j.mtcomm.2024.108248

Materials Today Communications

2024

DOI: 10.1016/j.mtcomm.2024.108248

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Alginate hydrogel incorporating cellulose nanofiber from solid waste agar industry for hydrophobic antibiotic delivery: Synthesis and characterization

Budiono Ujaya Putra,

Safrina Dyah Hardiningtyas,

Novitri Hastuti

et al.

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2024

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Cited by 3 publications

References 97 publications

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Applications of Functional Polymeric Eutectogels

Nicolau,

Mutch,

Thickett

2024

Macromol. Rapid Commun.

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Over the past two decades, deep eutectic solvents (DESs) have captured significant attention as an emergent class of solvents that have unique properties and applications in differing fields of chemistry. One area where DES systems find utility is the design of polymeric gels, often referred to as “eutectogels,” which can be prepared either using a DES to replace a traditional solvent, or where monomers form part of the DES themselves. Due to the extensive network of intramolecular interactions (e.g., hydrogen bonding) and ionic species that exist in DES systems, polymeric eutectogels often possess appealing material properties—high adhesive strength, tuneable viscosity, rapid polymerization kinetics, good conductivity, as well as high strength and flexibility. In addition, non‐covalent crosslinking approaches are possible due to the inherent interactions that exist in these materials. This review considers several key applications of polymeric eutectogels, including organic electronics, wearable sensor technologies, 3D printing resins, adhesives, and a range of various biomedical applications. The design, synthesis, and properties of these eutectogels are discussed, in addition to the advantages of this synthetic approach in comparison to traditional gel design. Perspectives on the future directions of this field are also highlighted.

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Applications of Functional Polymeric Eutectogels

Nicolau,

Mutch,

Thickett

2024

Macromol. Rapid Commun.

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Investigating the Antibacterial Effectiveness of Zinc Particles in Different Forms within Alginate-Based Hydrogels Incorporating Nanocellulose

Razi,

Timuda,

Khaerudini

et al. 2024

J Clust Sci

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Synthesis and Characterization of Ulvan-Alginate Hydrogel Beads as a Scaffold for Probiotic Immobilization

Ramadhan,

Ramadhani,

Sevica

et al. 2024

BIO Web Conf.

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Probiotic drinks have various benefits for the digestive tract. However, there is a problem with ensuring the viability of probiotics and their functionality while passing through the digestive tract to the large intestine, thus an alternative strategy is needed to maintain the viability of probiotics, namely hydrogel encapsulation of natural biopolymers such as ulvan and alginate. Hydrogels constructed from ulvan and alginate were predicted to be suitable for the challenge as a probiotic bioreactor that could stimulate human digestive health because its porosity and retention capacity could be chemically controlled. The aims of the study were to evaluate the characteristics of the selected ulvan concentrations and to determine the resistance of encapsulated probiotic bacteria in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). The research involved characterizing the hydrogel using different concentrations of ulvan (1%, 2%, 3%, and 4%) along with 2% alginate. Ulvan-alginate hydrogel produced the highest gel fraction and swelling ratio of 98.8% and 19.7%. The hydrogel system composed of 1% ulvan and 2% alginate effectively preserved the viability of probiotic bacteria in both SGF and SIF environments, with survival rates of 3.41 × 107 and 0.14 × 107 log CFU/g, respectively.

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Alginate hydrogel incorporating cellulose nanofiber from solid waste agar industry for hydrophobic antibiotic delivery: Synthesis and characterization

Cited by 3 publications

References 97 publications

Applications of Functional Polymeric Eutectogels

Applications of Functional Polymeric Eutectogels

Investigating the Antibacterial Effectiveness of Zinc Particles in Different Forms within Alginate-Based Hydrogels Incorporating Nanocellulose

Synthesis and Characterization of Ulvan-Alginate Hydrogel Beads as a Scaffold for Probiotic Immobilization

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