Alginate-based hydrogels prepared via ionic gelation: An experimental design approach to predict the crosslinking degree

Dodero, Andrea; Lara, Pianella; Vicini, Silvia; Alloisio, Marina; Ottonelli, Massimo; Castellano, Maila

doi:10.1016/j.eurpolymj.2019.06.028

Cited by 99 publications

(64 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1a. SA is usually extracted from the cell walls of brown algae and nowadays widely employed in several fields, ranging from biomedical applications to the restoration of cultural heritage (Lee and Mooney 2012;Sun et al 2013;Vicini et al 2015;Castellano et al 2019;Dodero et al 2019aDodero et al , 2020a.…”

Section: Introductionmentioning

confidence: 99%

Rheological properties of sodium alginate solutions in the presence of added salt: an application of Kulicke equation

et al. 2020

Self Cite

View full text Add to dashboard Cite

Mark-Houwink parameters are determined for sodium alginate with low (SA LV) and medium (SA MV) molecular mass via a rheological approach. Firstly, salt screening concentration and polyelectrolyte nature of the polymers are investigated. Despite both alginates behaving as neutral polymer in θ solvent, differences are observed between them with the strong associative nature of SA MV highlighted by an abnormal high viscosity concentration dependence compared with the predicted values. The polysaccharide-specific hydrodynamic volume (i.e., intrinsic viscosity) is determined via Fedors approach, which is proved to provide accurate results applicable to a wide concentration range. A viscosity-molecular mass-concentration relationship is finally derived to calculate Mark-Houwink parameters via a non-linear regression according to Kulicke equation; the obtained values are consistent with those reported in literature, confirming the semi-flexible nature of SA in the investigated environment and proving the effectiveness of the proposed approach for polyelectrolytes with added salt ions.

show abstract

Section: Introductionmentioning

confidence: 99%

Rheological properties of sodium alginate solutions in the presence of added salt: an application of Kulicke equation

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…In this regard, the design of the experiment is considered an encouraging approach to achieve this kind of knowledge, as it is able to evaluate simultaneously the influence of several variables and, above all, the existence of synergic or opposite interactions between them. In particular, by investigating the system response in well-defined points of the experimental domain, it is then possible to compute the obtained data to derive a mathematical model able to describe the property of interest within all of the variable ranges [38][39][40][41][42][43].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the Mechanical and Dynamic-Mechanical Properties of Electrospun Polyvinylpyrrolidone Membranes: A Design of Experiment Approach

et al. 2020

Self Cite

View full text Add to dashboard Cite

Polyvinylpyrrolidone electrospun membranes characterized by randomly, partially, or almost completely oriented nanofibers are prepared using a drum collector in static (i.e., 0 rpm) or rotating (i.e., 250 rpm or 500 rpm) configuration. Besides a progressive alignment alongside the tangential speed direction, the nanofibers show a dimension increasing with the collector rotating speed in the range 410–570 nm. A novel design of experiment approach based on a face-centred central composite design is employed to describe membrane mechanical properties using the computation of mathematical models and their visualization via response surface methodology. The results demonstrate the anisotropic nature of the fibre-oriented membranes with Young’s modulus values of 165 MPa and 71 MPa parallelly and perpendicularly to the alignment direction, respectively. Above all, the proposed approach is proved to be a promising tool from an industrial point of view to prepare electrospun membranes with a tailored mechanical response by simply controlling the collector speed.

show abstract

“…These divalent cations form a chelated structure, according to the commonly called egg-box model, preferentially with the GG blocks, thereby creating a stable three-dimensional network [8]. Alginate has potential in applications such as biomedicine, pharmaceutics, food industry, textiles, and additive manufacturing [9].…”

Section: Introductionmentioning

confidence: 99%

Influence of Process Parameters in Graphene Oxide Obtention on the Properties of Mechanically Strong Alginate Nanocomposites

et al. 2020

View full text Add to dashboard Cite

Sodium alginate, a biopolymer extracted from brown algae, has shown great potential for many applications, mainly due to its remarkable biocompatibility and biodegradability. To broaden its fields of applications and improve material characteristics, the use of nanoreinforcements to prepare nanocomposites with enhanced properties, such as carbonaceous structures which could improve thermal and mechanical behavior and confer new functionalities, is being studied. In this work, graphene oxide was obtained from graphite by using modified Hummers' method and exfoliation was assisted by sonication and centrifugation, and it was later used to prepare sodium alginate/graphene oxide nanocomposites. The effect that different variables, during preparation of graphene oxide, have on the final properties has been studied. Longer oxidation times showed higher degrees of oxidation and thus larger amount of oxygen-containing groups in the structure, whereas longer sonication times and higher centrifugation rates showed more exfoliated graphene sheets with lower sizes. The addition of graphene oxide to a biopolymeric matrix was also studied, considering the effect of processing and content of reinforcement on the material. Materials with reinforcement size-dependent properties were observed, showing nanocomposites with large flake sizes, better thermal stability, and more enhanced mechanical properties, reaching an improvement of 65.3% and 83.3% for tensile strength and Young's modulus, respectively, for a composite containing 8 wt % of graphene oxide.

show abstract

Alginate-based hydrogels prepared via ionic gelation: An experimental design approach to predict the crosslinking degree

Cited by 99 publications

References 39 publications

Rheological properties of sodium alginate solutions in the presence of added salt: an application of Kulicke equation

Rheological properties of sodium alginate solutions in the presence of added salt: an application of Kulicke equation

Investigation of the Mechanical and Dynamic-Mechanical Properties of Electrospun Polyvinylpyrrolidone Membranes: A Design of Experiment Approach

Influence of Process Parameters in Graphene Oxide Obtention on the Properties of Mechanically Strong Alginate Nanocomposites

Contact Info

Product

Resources

About